李扬

职称：讲师

邮箱：li_yang@sdau.edu.cn

个人主页：

https://www.researchgate.net/profile/Yang-Li-660

个人简介

李扬，男，汉族，博士，硕士生导师，主要从事母仔猪营养与饲养相关研究工作，研究方向包括：母猪繁殖力的营养调控、母体营养与胎儿程序化、畜禽肠道健康及营养调控技术、饲料资源的开发与利用等。承担本科生《动物营养学》、《动物营养学实验》、《饲料分析》、《动物营养与饲料科学》和《动物营养与饲料教学实习》等课程的教学。主持国家自然科学基金青年项目、山东省自然科学基金青年项目、十四五国家重点研发计划子课题1项、校级教学改革研究项目1项、横向课题1项；作为主要参与人参研国家自然科学基金2项，省部级项目2项、市级项目2项；荣获国家发明专利3件；参与制定团体标准3项；以第一作者和通讯作者在《Microbiology Spectrum》、《Animal Feed Science and Technology》、《International Journal of Molecular Sciences》、《Frontiers in Microbiology》、《Journal of Animal Science》等杂志发表SCI论文20余篇。现为《Frontiers in Immunology》、《Frontiers in Cellular and Infection Microbiology》和《Toxins》杂志客座编委，担任《mSystems》、《Food & Function》、《Gene》、《Journal of Animal Science》等杂志审稿专家。

教育经历

2023.08-至今，博士后，动物与人类健康工程，比利时荷语鲁汶大学

2021.12 - 至今, 博士后, 动物营养与饲料科学, 山东农业大学

2012.09 – 2019.12 , 农学博士 , 动物营养与饲料科学 , 四川农业大学

2008.09 – 2012.06 , 农学学士 , 动物科学 , 华南农业大学

工作经历

2020 - 至今 , 讲师 , 山东农业大学

2019 - 2020 , 配方师 , 双胞胎（集团）股份有限公司

承担的科研项目

1. 5-HTR/PI3K/Akt信号途径介导血清素调控猪胎盘血管生成的分子机制（国家自然科学基金青年项目，32302784，2024.01-2026.12，主持）

2. 5-羟基色氨酸对妊娠母猪繁殖性能的影响及其对胎盘发育和功能的调控作用研究（山东省自然科学基金青年项目，ZR2022QC084，2023.01-2025.12，主持）

3. 生物环境对泌乳母猪乳房炎及后代健康的影响及营养调控技术（十四五重点研发计划“种畜禽健康生产环境控制技术”子课题，2023YFD1300803，2023.12-2028.11，主持）

4. 课程思政视域下《饲料分析》教学设计与实践(校级面上教学改革研究项目，2024.01-2025.12，主持)

5. 博普总碱散、米伽酸和五倍子提取物对肉鸡生长性能、肠道发育和盲肠菌群组成的影响研究（横向课题，2021.09-2022.09，主持）

6. 母猪饲粮纤维在后肠促进褪黑素生成进而提高繁殖性能的机制研究（国家自然科学基金，2019.01-2021.12，参与）

7. mTORC1信号通路介导精氨酸调控公猪精原干细胞增殖的作用机制研究（国家自然科学基金，2018.01-2020.12，参与）

8. 主要畜禽标准化养殖技术研究与示范（四川省科技支撑计划，参与）

9. 发酵饲料营养配比优化提升（教育部协同育人项目，参与）

10. SPF鸡繁育及配套生产关键技术集成与推广（济南市重点研发项目，参与）

发表文章、专利

1.Yang Liu, Kai Han, Hua Liu, Gang Jia, Luke Comer, Guanlin Wang, Zizhu Pan, Yiqian Zhao, Shuzhen Jiang, Ning Jiao, Libo Huang, Weiren Yang, Yang Li *. Macleaya cordata isoquinoline alkaloids attenuate Escherichia coli lipopolysaccharide-induced intestinal epithelium injury in broiler chickens by co-regulating the TLR4/MyD88/NF-κB and Nrf2 signaling pathways. Frontiers in Immunology, 2023, 14.

2.Peng Yuan,Xiaojie Ren, Jiaxing Niu, Yang Liu, Libo Huang, Shuzhen Jiang, Ning Jiao, Xuejun Yuan, Weiren Yang, Yang Li *. Effects of dietary Galla Chinensis tannin supplementation on antioxidant capacity and intestinal microbiota composition in broilers. Agriculture, 2023, 13, 1780. 

3.Hengchen Liu, Jianli Sun, Shuzhen Jiang, Ning Jiao, Libo Huang, Xuejun Yuan, Qinglin Guan, Yang Li*, Weiren Yang*. Effects of dietary isoleucine supplementation on the production performance, health status and cecal microbiota of Arbor Acre broiler chickens. Microorganisms, 2023, 11(2):236.

4.Peng Yuan, Haitao Xu, Yuanfei Ma, Jiaxing Niu, Yang Liu, Libo Huang, Shuzhen Jiang, Ning Jiao, Xuejun Yuan, Weiren Yang*, Yang Li*. Effects of dietary Galla Chinensis tannin supplementation on immune function and liver health in broiler chickens challenged with lipopolysaccharide. Frontiers in Veterinary Science, 2023,10:1126911.

5.Yang Li, Min Yang, Lijia Zhang, Zhengyu Mao, Yan Lin, Shengyu Xu, Zhengfeng Fang, Lianqiang Che, Bin Feng, Jian Li, Yong Zhuo*, De Wu*. Dietary fiber supplementation in gestating sow diet improved fetal growth and placental development and function through serotonin signaling pathway. Frontiers in Veterinary Science, 2022, 9.

6.Yang Liu, Qinjin Wang, Hua Liu, Jiaxing Niu, J Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang*, Yang Li*. Effects of dietary Bopu powder supplementation on intestinal development and microbiota in broiler chickens. Frontiers in Microbiology, 2022, 13: 975056.

7.Junwei Li, Yang Liu, Jiaxing Niu, Changwei Jing, Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang*, Yang Li*. Supplementation with paraformic acid in the diet improved intestinal development through modulating intestinal inflammation and microbiota in broiler chickens. Frontiers in Microbiology, 2022, 13: 3515.

8.Jiaxing Niu, Qinjin Wang, Changwei Jing, Yang Liu, Hua Liu, Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang*, Yang Li*. Dietary Galla Chinensis tannic acid supplementationin the diets improves growth performance, immune function and liver health status of broiler chicken. Frontiers in Veterinary Science, 2022, 9:1024430.

9.Qinjin Wang, Jiaxing Niu, Yang Liu, Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang, Yang Li *. Supplementation of paraformic acid as a substitute for antibiotics in the diet improves growth performance and liver health in broiler chickens. Animals, 2022, 12(20): 2825.

10.Changwei Jing, Jiaxing Niu, Yang Liu, Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang*, Yang Li*. Tannic acid extracted from Galla chinensis supplementation in the diet improves intestinal development through suppressing inflammatory responses via blockage of NF-κB in broiler chickens. Animals, 2022, 12(18):2397.

11.Yang Liu, Yang Li*, Jiaxing Niu, Hua Liu, Ning Jiao, Libo Huang, Shuzhen Jiang, Weiren Yang*. Effects of dietary Macleaya Cordata extract containing isoquinoline alkaloids supplementation as an alternative to antibiotics in the diets on growth performance and liver health of broiler chickens. Frontiers in Veterinary Science, 2022, 950174.

12.Yang Li, Jiaqi He, Lijia Zhang, Haoyu Liu, Meng Cao, Yan Lin, Shengyu Xu, Zhengfeng Fang, Lianqiang Che, Bin Feng, Xuemei Jiang, Jian Li, Yong Zhuo*, De Wu*. Effects of dietary fiber supplementation in gestation diets on sow performance, physiology and milk composition for successive three parities. Animal Feed Science and Technology, 2021, 276: 114945.

13.Jiali Chen, Fuchang Li, Weiren Yang, Shuzhen Jiang, Yang Li*. Supplementation with exogenous catalase from penicillium notatum in the diet ameliorates lipopolysaccharide-induced intestinal oxidative damage through affecting intestinal antioxidant capacity and microbiota in weaned pigs. Microbiology spectrum, 2021, 9(3): e00654-21.

14.Jiali Chen, Fuchang Li, Weiren Yang, Shuzhen Jiang, Yang Li*. Comparison of gut microbiota and metabolic status of sows with different litter sizes during pregnancy. Frontiers in veterinary science, 2021, 8.

15.Pengfei Zhang, Changwei Jing, Ming Liang, Shuzhen Jiang, Libo Huang, Ning Jiao, Yang Li*, Weiren Yang*. Zearalenone exposure triggered cecal physical barrier injury through the TGF-β1/smads signaling pathway in weaned piglets. Toxins, 2021, 13(12): 902.

16.Yang Li, Haoyu Liu, Lijia Zhang, Yi Yang, Yan Lin, Yong Zhuo, Zhengfeng Fang, Lianqiang Che, Bin Feng, Shengyu Xu, Jian Li, De Wu*. Maternal dietary fiber composition during gestation induces changes in antioxidative capacity, inflammatory response and gut microbiota of their offspring in a sow model. International Journal of Molecular Sciences, 2020, 21(1): 31.

17.Yang Li, Xilun Zhao, Lijia Zhang, Xiaoyan Zhan, Zhiguo Liu, Yong Zhuo, Zhengfeng Fang, Lianqiang Che, Bin Feng, Shengyu Xu, Jian Li, De Wu*. Effects of a diet supplemented with exogenous catalase from penicillium notatum on intestinal development and microbiota in weaned piglets. Microorganisms 2020, 8(3), 391.

18.Yang Li, Xilun Zhao, Xuemei Jiang, Yi Yang, Jiaqi He, Meng Cao, Wei Zhong, Yan Lin, Yong Zhuo, Zhengfeng Fang, Lianqiang Che, Bin Feng, Shengyu Xu, Jian Li, Xilun Zhao, Xuemei Jiang, De Wu*. Effects of dietary supplementation with exogenous catalase on growth performance, oxidative stress and hepatic apoptosis in weaned piglets challenged with lipopolysaccharide. Journal of Animal Science, 2020, 98(3):skaa067.

19.Yang Li, Lijia Zhang, Haoyu Liu, Yi Yang, Jiaqi He, Meng Cao, Min Yang, Zhong Wei, Yan Lin, Yong Zhuo, Zhengfeng Fang, Lianqiang Che, Bin Feng, Shengyu Xu, Jian Li, Xilun Zhao, Xuemei Jiang, De Wu*. Effects of the ratio of insoluble fiber to soluble fiber in gestation diets on sow performance and offspring intestinal development. Animals, 2019, 9(7), 422.

20.Yan Lin +,*, Lujie Li+, Yang Li+, Ke Wang, Dongqin Wei, Shengyu Xu, Bin Feng, Lianqiang Che, Zhengfeng Fang, Jian Li, Yong Zhuo, De Wu*. Interpretation of fiber supplementation on offspring testicular development in a pregnant sow model from a proteomics perspective. International Journal of Molecular Sciences, 2019, 20: 4549.

21.Yang Li, Ling Chen, Yuhui Zhang, Jianmei Wu, Yan Lin, Zhengfeng Fang, Lianqiang Che, Shengyu Xu, De Wu*. Substitution of soybean meal with detoxified Jatropha curcas kernel meal: Effects on performance, nutrient utilization, and meat edibility of growing pigs. Asian-Australasian Journal of Animal Sciences, 2018, 31(6): 888.

22.Yang Li, Ling Chen, Yan Lin, Zhengfeng Fang, Lianqiang Che, Shengyu Xu, De Wu. Effects of replacing soybean meal with detoxified Jatropha curcas kernel meal in the diet on growth performance and histopathological parameters of growing pigs. Animal Feed Science and Technology, 2015, 204: 18-27.

23.Xing Chen, Xiangming Ma, Chongwu Yang, Shuzhen Jiang, Libo Huang, Yang Li, Fan Zhang, Ning Jiao*, Weiren Yang*. Low level of dietary organic trace elements improve the eggshell strength, trace element utilization, and intestinal function in late-phase laying hens. Frontiers in Veterinary Science, 2022, 9.

24.Boyang Wan, Libo Huang, Changwei Jing, Yang Li, Ning Jiao, Ming Liang, Shuzhen Jiang, Weiren Yang*. Zearalenone promotes follicle development through activating the SIRT1/PGC-1α signaling pathway in the ovaries of weaned gilts. Journal of Animal Science, 2022, 100(4): skac058.

25.Quanwei Zhang, Libo Huang, Bo Leng, Yang Li, Ning Jiao, Shuzhen Jiang, Weiren Yang*, Xuejun Yuan*. Zearalenone affect the intestinal villi associated with the distribution and the expression of ghrelin and proliferating cell nuclear antigen in weaned gilts. Toxins, 2021, 13(10): 736.

26.Boyang Wan, Xuejun Yuan, Weiren Yang, Ning Jiao, Yang Li, Faxiao Liu, Mei Liu, Zaibin Yang, Libo Huang *, Shuzhen Jiang*. The effects of zearalenone on the localization and expression of reproductive hormones in the ovaries of weaned gilts. Toxins, 2021, 13(9): 626.

27.Daolin Mou, Shuang Li, Chuan Yan, Qianqian Zhang, Jing Li, Qiujie Wu, Peng Qiu, Yang He, Yang Li, Haoyu Liu, Xuemei Jiang, Yong Zhuo, Bin Feng, Yan Lin, Zhengfeng Fang, Shengyu Xu, Jian Li, Lianqiang Che*, De Wu*. Dietary fiber sources for gestation sows: Evaluations based on combined in vitro and in vivo methodology. Animal Feed Science and Technology, 2020, 269.

28.Yong Zhuo, Meng Cao, Lechan Gong, Lianchao Tang, Xuemei Jiang, Yang Li, Min Yang, Shengyu Xu, Jian Li, Lianqiang Che, Yan Lin, Bin Feng, Zhengfeng Fang, De Wu*. Gut microbial metabolism of dietary fiber protects against high-energy feeding induced ovarian follicular atresia in a pig model. British Journal of Nutrition, 2020: 1-35.

29.Meng Cao, Yong Zhuo*, Lechan Gong, Lianchao Tang, Zhipeng Li, Yang Li, Min Yang, Shengyu Xu, Jian Li, Lianqiang Che, Yan Lin, Bin Feng, Zhengfeng Fang, De Wu*. Optimal dietary fiber intake to retain a greater ovarian follicle reserve for gilts. Animals, 2019, 9(11): 881.

30.姜淑贞，杨维仁，朱应波，李肖，周华杰，黄丽波，袁学军，李扬，焦宁，姜艳萍，牛加兴. 一种甜高粱和田菁混合青贮饲料及其制备方法和应用. 中国发明专利，2023.

31.吴德，李扬，方正锋，车炼强，徐盛玉，林燕，冯斌，李建，陈玲，赵希仑. 一种促进母猪胚胎着床的功能性预混剂. 中国发明专利，2020.

32.吴德，李扬，方正锋，车炼强，徐盛玉，林燕，冯斌，李建，陈玲，赵希仑. 一种提高母猪发情的微生态制剂及制备方法和应用. 中国发明专利，2019.

33.T/SDFA 003《青贮全株玉米生产与生猪饲喂规范》，团体标准，山东省饲料行业协会,  2021.

34.T/SDFA 039 《莱芜猪饲养技术规范》，团体标准，山东省饲料行业协会/山东省畜牧协会，2023.

35.T/SDFA 002 《发酵饲料原料》，团体标准，山东省饲料行业协会,  2023.

荣誉奖励

1. 2022年山东省研究生创新成果专业学位三等奖（指导教师）

2. 2022年中国·山东博士后创新创业大赛泰安赛区创新组一等奖

3. 2022年中国·山东博士后创新创业大赛创新组优秀项目

4. 2022年岱岳区第二届高层次人才创新创业大赛产业创新类二等奖

5. 山东农业大学2023届优秀学士学位论文“博普总碱对LPS诱导的肉鸡肠道炎性反应的缓解作用研究“（指导教师）

6. 2022年山东农业大学大学生节能减排社会实践与科技竞赛优秀奖（指导教师）