浏览次数：15138
姓名：兰江风
职称：教授/博士生导师
邮箱：jflan@sdau.edu.cn; sjs15@163.com
办公室电话：13871570938
个人简介
兰江风，男，教授，博士生导师，山东农业大学“1512”第二层次。2014年毕业于山东大学动物学专业，获理学博士学位。2014-2020年在华中农业大学水产学院工作。2017-2018年耶鲁大学医学院访问学者。主持国家/省自然科学基金，参与国家/省重点研发计划等国家及省部级项目。一直从事水生无脊椎动物病害防控研究，研究成果主要发表在领域Top或JCR 1区杂志：Plos Pathogens (病原学Top)，Journal of Virology (病毒学Top)，Fish Shellfish Immunol. (农林大类1区)，Dev Comp Immunol.（动物学1区）, Frontiers in Immunology等，获批专利10余项。
教育经历
2009 - 2014, 理学博士 , 动物学 , 山东大学生命科学学院
2005 - 2009 , 理学学士 , 生物技术 , 湖南科技大学生命科学学院
工作经历
2021 - 至今 , 教授 ,山东农业大学动物科学学院/动物医学院
2017 - 2021 , 副教授 ,华中农业大学水产学院
2017 - 2018，访问学者,耶鲁大学医学院
2014 - 2017 , 讲师 ,华中农业大学水产学院
荣誉奖励
华中农业大学水产学院拔尖人才（2016）
华中农业大学硕彦英才A类（2018）
执教课程
水产动物免疫学（本科生）
水生动物病原生物学、现代渔业进展（研究生）
研究领域
1. 水生动物先天免疫
2. 虾蟹主要病原的致病机制
3. 病害生态防控
在研项目
山东农业大学高层次人才启动经费2021-2025
国家重点研发计划，虾-稻综合种养关键技术与综合利用模式示范2020.10-2022.12
代表专利
1.兰江风、张英豪、李通、曹晓彤、殷成明、顾泽茂；一种克氏原螯虾抗脂多糖因子gALF1基因及其编码的gALF1蛋白及其应用；发明专利，授权号ZL201911184929.3，授权日：2022.1.13.
2. 兰江风、张英豪、李通、曹晓彤、殷成明、顾泽茂：一种克氏原螯虾i型溶菌酶gLysi2基因、其编码的蛋白及其应用; 发明专利，授权号：ZL201910809933.8，授权日：2022.1.06.
3. 兰江风、顾泽茂、张英豪、李通、曹晓彤、孙萌；一种克氏原螯虾C型凝集素gLecB基因及其编码的gLecB蛋白；发明专利，授权号ZL201910416443.1，授权日：2021.6.03.
4. 王金星、兰江风、赵小凡；克氏原螯虾抑制素1基因及其编码的抑制素1蛋白及其应用；发明专利，授权号：ZL201310289986.4，授权日: 2014.11.26.
5. 介邓飞、叶章颖、朱松明、张顺、兰江风、魏萱; 一种基于LED光谱的虾养殖试验装置，实用新型专利，专利号：ZL201721409084.X, 授权日：2018.6.15.
6. 介邓飞、叶章颖、朱松明、张顺、邹东波、史世杰、刘宇涵、周万怀、兰江风；一种大闸蟹公母和大小在线无损检测分级设备；实用新型专利，专利号：ZL201720581126.1，授权日：2018.01.02.
代表文章
1. Cao XT, Pan XY, Sun M, Liu Y, Lan JF*，Hepatopancreas-specific lectin participates in the antibacterial immune response by regulating the expression of antibacterial proteins. Frontiers in Immunology. 2021 May 31. JCR 2区, IF=8.786
2. Yin CM, Pan XY, Cao XT, Li T, Zhang YH*, Lan JF*, A crayfish ALF inhibits the proliferation of microbiota by binding to RPS4 and MscL of E. coli, Dev Comp Immunol. 2021 Apr 17;104106. JCR 1区, IF=3.636
3. Yin CM, Li NQ, Ren LC, Wang Z, Chai LQ*, Lan JF1*. Identification and characterization of two highly homologous lysozymes from red swamp crayfish, Procambarus clarkii. Fish and Shellfish Immunology Reports. 2021. July.
4. Liu Y, Zhang YH, Li T, Cao XT, Zhou Y, Yuan JF, Gu ZM, Lan JF*.PcLys-i3, an invertebrate lysozyme, is involved in the antibacterial immunity of the red swamp crayfish, Procambarus clarkii. Dev Comp Immunol. 2018 May 31;87:109-115. JCR 1区, IF=3.636
5. Qin Z, Babu VS, Wan Q, Zhou M, Liang R, Muhammad A, Zhao L, Li J, Lan JF*, Lin L*. Transcriptome analysis of Pacific white shrimp (Litopenaeus vannamei) challenged by Vibrio parahaemolyticus reveals unique immune-related genes. Fish Shellfish Immunol. 2018 Mar 19. pii: S1050-4648. JCR 1区, IF=4.632.
6. Qin Z, Babu VS, Wan Q, Muhammad A, Li J, Lan JF*, Lin L*. Antibacterial activity of hemocyanin from red swamp crayfish (Procambarus clarkii). Fish Shellfish Immunol. 2018 Feb 7;75:391-399. JCR 1区, IF=4.632.
7. Sun JJ1, Lan JF1, Zhao XF, Vasta N, Wang JX*, Binding of a C-type lectin's coiled-coil domain to the Domeless receptor directly activates the JAK/STAT pathway in the shrimp immune response to bacterial infection. PLoS Pathog. 2017 Sep 20;13(9):e1006626. doi: 10.1371/journal.ppat.1006626. JCR 2区，IF=7.464.
8. Zhou J, Zhao S, Fang WH, Zhou JF, Zhang JX, Ma H, Lan JF*, Li XC*. Newly identified invertebrate-type lysozyme (Splys-i) in mud crab (Scylla paramamosain) exhibiting muramidase-deficient antimicrobial activity. Dev Comp Immunol. 2017 Sep;74:154-166. JCR1区，IF=3.636.
9. Dai YJ, Hui KM, Zhang YH, Liu Y, Wang YQ, Zhao LJ, Lin L, Chai LQ, Wei Shun*, Lan JF*. Three STATs are involved in the regulation of the expression of Antimicrobial peptides in the Triangle sail mussel, Hyriopsis cumingii. Fish Shellfish Immunol. 2017 Feb, 63: 181-188. JCR 1区, IF=4.632.
10. Dai YJ, Wang YQ, Zhang YH, Liu Y, Li JQ, Wei S, Zhao LJ, Zhou YC, Lin L*, Lan JF*. The role of ficolin-like protein (PcFLP1) in the antibacterial immunity of red swamp crayfish (Procambarus clarkii). Mol Immunol., 2017, 81: 26-34. JCR 3区，IF=4.2.
11. Lan JF, Zhao LJ, Wei S, Wang Y, Lin L, Li XC*. PcToll2 positively regulates the expression of antimicrobial peptides by promoting PcATF4 translocation into the nucleus. Fish Shellfish Immunol. 2016 Sep 10;58:59-66. JCR 1区, IF=4.632.
12. Lan JF, Wei S, Wang YQ, Dai YJ, Tu JG, Zhao LJ, Li XC, Qin QW, Chen N*, Lin L*. PcToll3 was involved in anti-Vibrio response by regulating the expression of antimicrobial peptides in red swamp crayfish, Procambarus clarkii. Fish Shellfish Immunol, 2016 Aug 13, 57 : 17-24. JCR 1区, IF=4.632.
13. Sun JJ, Lan JF*, Xu JD, Niu GJ, Wang JX*. Suppressor of cytokine signaling 2 negatively regulates the expression of antimicrobial peptides by affecting the Stat transcriptional activity in shrimp Marsupenaeus japonicus. Fish Shellfish Immunol. 2016 Aug 2;56:473-482. JCR 1区, IF=4.632.
14. Wang Y, Chen N, Abeer M. Hegazy, Liu XD, Wu ZX , Liu XQ, Zhao LJ, Qin QW, Lan JF*, Lin L*. Autophagy induced by Snakehead fish vesiculovirus inhibited its replication in SSN-1 cell line. Fish Shellfish Immunol, 2016 Jun 13;55:415-422. JCR 1区, IF=4.632.
15. Zhao LL, Wang YQ, Dai YJ, Zhao LJ, Qin QW, Lin L, Ren Q*, Lan JF*. A novel C-type lectin with four CRDs is involved in the regulation of antimicrobial peptide gene expression in Hyriopsis cumingii. Fish Shellfish Immunol, 2016 Jun 7;55:339-347. JCR 1区, IF=4.632.
16. Zhao LL, Jin M, Li XC, Ren Q*, Lan JF*. Four C1q domain-containing proteins involved in the innate immune response in Hyriopsis cumingii. Fish Shellfish Immunol. 2016 Jun 7;55:323-331. JCR 1区, IF=4.632.
17. Dai YJ, Wang YQ, Zhao LL, Qin ZD, Yuan JF, Qin QW, Lin L*, Lan JF*. A novel L-type lectin was required for the multiplication of WSSV in red swamp crayfish (Procambarus clakii). Fish Shellfish Immunol, 2016 May 18;55:48-55. JCR 1区, IF=4.632.
18. Tu JG, Chen WJ, Fu XZ, Lin Q, Chang OQ, Zhao LJ, Lan JF*, Li NQ*, Lin L*.Susceptibility of Chinese perch brain (CPB) cell and Mandarin fish to Red-spotted grouper nervous necrosis virus (RGNNV) infection. Int J Mol Sci. 2016 May 19;17(5). pii: E740. JCR 2区，IF=6.208.
19. Wang Z, Chen YH, Dai YJ, Tan JM, Huang Y, Lan JF*, Qian Ren*.A novel vertebrates Toll-like receptor counterpart regulating the anti-microbial peptides expression in the freshwater crayfish, Procambarus clarkii. Fish Shellfish Immunol. 2015 Jan 5;43(1):219-229. JCR 1区, IF=4.632.
20. Ding ZF, Ren J, Tan JM, Wang Z, Yin SW, Huang Y, Huang X, Wang W, Lan JF*, Qian Ren*.Characterization of two novel ADP ribosylation factors from giant freshwater prawn Macrobrachium rosenbergii and their responses to WSSV challenge. Dev Comp Immunol. 2015 Jan;48(1):204-9. JCR 1区，IF=3.6.
21. Liu N1, Lan JF1, Sun JJ1, Jia WM, Zhao XF, Wang JX*.A novel crustin from Marsupenaeus japonicus promotes hemocyte phagocytosis. Dev Comp Immunol. 2014 Dec 3;49(2):313-322. JCR 1区，IF=3.636.
22. Ren Q1*, Lan JF1, Zhong X, Song XJ, Ma F, Hui KM, Wang W, Yu XQ*, Wang JX*. A novel Toll like receptor with two TIR domains (HcToll-2) is involved in regulation of antimicrobial peptide gene expression of Hyriopsis cumingii. Dev Comp Immunol. 2014 Jul;45(1):198-208. JCR 1区，IF=3.6.
23. Zhu L1, Lan JF1, Huang YQ, Zhang C, Zhou JF, Fang WH, Yao XJ, Wang H, Li XC*. SpALF4: a newly identified anti-lipopolysaccharide factor from the mud crab Scylla paramamosain with broad spectrum antimicrobial activity. Fish and Shellfish Immunology. 2014 Jan;36(1):172-80. JCR 1区, IF=4.632.
24. Lan JF, Zhou J, Zhang XW, Wang ZH, Zhao XF, Ren Q*, Wang JX*. Characterization of an immune deficiency homolog (IMD) in shrimp (Fenneropenaeus chinensis) and crayfish (Procambarus clarkii). Dev Comp Immunol. 2013 Dec;41(4):608-17. JCR 1区，IF=3.636.
25. Lan JF, Li XC, Sun JJ, Gong J, Wang XW, Shi XZ, Shi LJ, Weng YD, Zhao XF, Wang JX*. Prohibitin Interacts with envelope proteins of white spot syndrome virus and prevents infection in the red swamp crayfish, Procambarus clarkii. J Virol. 2013 Dec;87(23):12756-65. JCR 2区，IF=6.549.
26. Du ZQ1, Lan JF1, Weng YD, Zhao XF, Wang JX*. BAX inhibitor-1 silencing suppresses white spot syndrome virus replication in red swamp crayfish, Procambarus clarkii. Fish Shellfish Immunol. 2013 Jul;35(1):46-53. JCR 1区, IF=4.632.
27. Sun JJ, Lan JF, Shi XZ, Yang MC, Niu GJ, Ding D, Zhao XF, Yu XQ, Wang JX*. β-Arrestins Negatively Regulate the Toll Pathway in Shrimp by Preventing Dorsal Translocation and Inhibiting Dorsal Transcriptional Activity. J Biol Chem. 2016 Apr 1;291(14):7488-504. JCR 2区, IF= 5.486.
28. Yang J, Schleicher TR, Dong Y, Park HB, Lan JF, Cresswell P, Crawford J, Dimopoulos G, Fikrig E. Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection. J Exp Med. 2020 Jan 6;217(1):e20190682. JCR 1区, IF= 17.579.
29. Ren Q, Wang C, Jin M, Lan JF, Ye T, Hui K, Tan J, Wang Z, Wyckoff GJ, Wang W, Han GZ.Co-option of bacteriophage lysozyme genes by bivalve genomes.
Open Biol. 2017 Jan;7(1):160285. doi: 10.1098/rsob.160285. JCR 2区, IF= 7.124.
30. 刘小玲，王虹，樊启学，兰江风*，林蠡*，黄颡鱼甘露糖受体基因的克隆和功能分析. 水产学报 2017, 41 (7)1036-08.
31. 兰江风, 代云佳, 林蠡*, 养殖克氏原螯虾体内白斑综合征病毒的绝对定量分析. 水产学报 2016，40 (3) 318-324.