刘磊

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刘磊

职称:副教授

邮箱:leiliu@sdau.edu.cn

个人简介

刘磊(1985-),男,博士,副教授,山东农业大学威尼斯wns·8885556动物营养与饲料科学系,硕士生导师。现任山东省特种经济动物产业技术体系泰安综合试验站站长,国家兔产业体系成员,中国畜牧兽医学会养兔学分会副秘书长、山东省家兔专家委员会副秘书长。主要从事家兔营养与家兔生产的研究,先后主持中国博士后基金面上资助项目、山东省自然科学基金等课题10余项。相关研究成果获得首届中国青年学者动物营养科技奖、山东省科技进步一等奖(参与)、山东省优秀博士学位论文;以第一或通讯作者发表论文70余篇,其中SCI论文收录30余篇;获得发明专利1项,实用新型专利2项,软件著作权1项。

教育经历

2011 - 2014 , 农学博士 , 基础兽医学专业 , 山东农业大学

2009 - 2011 , 农学硕士 , 动物营养与饲料科学专业 , 山东农业大学

2005 - 2009 , 农学学士 , 动物科学专业 , 山东农业大学

工作经历

2018 - 至今 , 副教授 , 山东农业大学

2018-2018,访问学者,美国北卡罗来纳州立大学

2015-2018 , 博士后 , 家兔营养 , 山东农业大学

2014 - 2018 , 讲师 , 山东农业大学

执教课程

动物生产学(禽、羊、兔)(本科生)

动物生产学综合实验(禽、羊、兔)(本科生)

动物生产学I(本科生)

动物生产学综合实验I(本科生)

动物生产I教学实习(本科生)

社会实践与调查报告(本科生)

动物分子营养与实验技术(研究生)

企业经营和技术创新实践(研究生)

研究领域

本实验室主要研究领域

1. 家兔营养需要量的研究及饲料原料营养价值评定

2.家兔无抗饲料及新型饲料添加剂的研发

3家兔毛囊发育机制及营养调控研究

3.家兔肠道微生物菌落规律及营养调控研究

承担的科研项目

1.山东省现代农业产业技术体系. 山东省特种经济动物产业体系(泰安综合试验站)(SDAIT-21-16). 时间2021.09-2026.06. 经费75万(主持)

2.山东省重点研发计划(农业良种工程)项目子课题. 优质高产肉兔新品种选育(2021LZG002. 时间2021.12-2024.12. 经费20万(主持)。

3.山东省自然科学基金面上项目. 基于BMP2信号研究维生素A对热应激獭兔毛囊发育的影响(ZR2021MC043). 时间2022.01-2024.12. 经费10万(主持)

4.山东省自然科学基金青年基金. 小肽转运载体在应激家兔寡肽吸收中的作用(ZR2018QC004. 时间2018.03-2020.12. 经费16万(主持)

5中国博士后基金面上资助. PepT1在应激家兔寡肽吸收中的作用 (2015M580601) . 时间2015.11-2018.03. 经费8万(主持)

6.山东省自然科学基金培养基金. AMPK信号在应激家禽对高能日粮偏嗜中的作用(ZR2014CP028).  时间2014.12-2016.12. 经费5万(主持)

7.山东省博士后创新项目. Wnt信号通路在铜调节热应激獭兔毛囊发育中的作用(2020). 时间2020-2022. 经费3万(主持)

8.现代农业产业技术体系. 国家兔产业技术体系岗位(CARS-43-B-1). 时间2021.01-2025.12. 经费350万(参与,第二位)

发表文章、专利

1.孙良展, 吴振宇, 李福昌, 王春阳, 朱岩丽, 刘磊, 张帝, 李京霖. 一种母兔笼. 实用新型专利.专利号:ZL201620822449.0

2.李福昌,刘磊. 一种兔用输精装置. 实用新型专利. 专利号:ZL201620560300.X

3.刘磊,李福昌. 兔子常见疾病诊断与防治信息库软件. 软件著作权. 登记号:2016S189416.

4.李福昌, 刘磊. 一种提高兔肉蛋白质含量的中草药饲料添加剂及制备方法. 发明专利。专利号:ZL201710100590.9

5. Liu HL, Zhang B, Li F, Liu L, Li FC. Shifts in the intestinal microflora of meat rabbits in response to glucocorticoids. Journal of the Science of Food and Agriculture. 2022 doi: 10.1002/jsfa.11895. (corresponding author)

6.Liu HL, Zhang B, Liu L, Li FC. Metabolomics research on the effect of dexamethasone-induced chronic stress in serum of rabbits. Italian Journal of Animal Science. 2022, 21(1): 188-197.  doi: 10.1080/1828051X.2021.2004937. (corresponding author)

7. Yue ZK, Li CY, Liu YX, Liu MQ, Zhao M, Li FC, Liu L. Vitamin A alleviates heat stress-induced damage to hair follicle development in Rex rabbits. Journal of the Science of Food and Agriculture. 2022. 102(6): 2291-2299. doi: 10.1002/jsfa.11567. (corresponding author)

8. Li  CY, Chen JL, Zhao  M, Liu  MQ, Yue  ZK, Liu  L, Li FC. Effect of sodium butyrate on slaughter performance, serum indexes and intestinal barrier of rabbits. Journal of Animal Physiology and Animal Nutrition. 2022. 106(1): 156-166. doi: 10.1111/jpn.13571. (corresponding author)

9. Liu M, Li C, Tang H, Gong M, Yue Z, Zhao M, Liu L, Li F. Dietary lysine supplementation improves growth performance and skeletal muscle development in rabbits fed a low protein diet. Journal of Animal Physiology and Animal Nutrition. 2021. doi: 10.1111/jpn.13632. (corresponding author)

10.Li YJ, Fu CY, Liu L, Liu YX, Li FC. mTOR and ERK1/2 signaling participate in the process of acetate regulatinglipid metabolism via regulating HSL expression. Animal Bioscience. 2021. doi: 10.5713/ab.21.0341. (corresponding author)

11.Li CY, Niu JL, Liu YX , Li FC, Liu L. The effects of oregano essential oil on production performance and intestinal barrier function in growing Hyla rabbits. Italian Journal of Animal Science. 2021. 20(1): 2165-2173. doi: 10.1080/1828051X.2021.2005471. (corresponding author)

12. Hu JQ, Li WQ, Qiao XB, Li WJ, Xie KR,Wang YY, Huang B, Zhao QY, Liu L, Fan XZ. Characterization of microRNA profiles in pasteurella multocida-infected rabbits and Identification of miR-29-5p as a regulator of antibacterial immune response. Frontiers In Veterinary Science. 2021. 8: 746638.  doi: 10.3389/fvets.2021.746638.  (corresponding author)

13. Liu L, Fu CY, Liu YX, Li FC. Acetate stimulates lipogenesis via AMPKαsignaling in rabbit adipose-derived stem cells. General and Comparative Endocrinology. 2021: 113715. doi: 10.1016/j.ygcen.2021.113715.   

14. Li CY, Chen XY, Zhang B, Liu L, Li FC. Sodium butyrate improved intestinal barrier in rabbits. Italian Journal of Animal Science. 2020, 19(1): 1472-1482. doi: org/10.1080/1828051X.2020.1847209 (corresponding author)

15. Liu H, Liu L, Li F. Effects of glucocorticoids on the gene expression of nutrient transporters in different rabbit intestinal segments. Animal. 2020 14(8), 1693-1700. doi: 10.1017/S1751731120000245. (corresponding author)

16. Liu L, Gao Q, Wang C, Fu ZH, Wang K, Li FC. High doses of cobalt inhibited hair follicle development in Rex Rabbits. World Rabbit Science. 2019, 27: 217-225. doi: 10.4995/wrs.2019.12038.

17. Liu L, Fu CY, Li FC. Acetate affects the process of lipid metabolism in rabbit liver, skeletal muscle and adipose tissue. Animals. 2019, 9, 799. doi: 10.3390/ani9100799.

18. Liu L, Zhao XY, Liu YX, Zhao H, Li FC. Dietary addition of garlic straw improved the intestinal barrier in rabbits. Journal of Animal Science. 2019. 97(10): 4248-4255. doi: 10.1093/jas/skz277.

19.Liu L, Zuo WS, Li FC. Dietary addition of artemisia argyi reduces diarrhea and modulates the gut immune function without impacting growth performances of rabbits after weaning. Journal of Animal Science. 2019. 97(4): 1693-1700. doi: 10.1093/jas/skz047.

20.Liu L, Liu H, Ning L, Li F. Rabbit SLC15A1, SLC7A1 and SLC1A1 genes are affected by site of digestion, stage of development and dietary protein content. Animal. 2019. 13(2): 326-332. doi: 10.1017/S1751731118001404.

21. Fu C, Liu L, Li F. Acetate alters the process of lipid metabolism in rabbits. Animal. 2018. 12(9): 1895-1902. doi: 10.1017/S1751731117003275. (corresponding author)

22.Liu L, Liu H, Fu C, Li C, Li F. Acetate induces anorexia via up-regulating the hypothalamic pro-opiomelanocortin (POMC) gene expression in rabbits. Journal of Animal and Feed Sciences. 2017. 26(3): 266-273. doi: 10.22358/jafs/75979/2017.

23. Fu CY, Liu L*, Gao Q, Sui XY, Li FC. Cloning, molecular characterization, and spatial and developmental expression analysis of GPR41 and GPR43 genes in New Zealand rabbits. Animal. 2017. 11(10):1798-1806. doi: 10.1017/S175173111700043X. (*co-first author)  

24.Liu L, Wang X, Jiao H, Lin H. Glucocorticoids induced high fat diet preference via activating hypothalamic AMPK signaling in chicks. General and Comparative Endocrinology. 2017. 249: 40-47.  doi: 10.1016/j.ygcen.2017.02.018.

25. Liu L, Sui XY, Li FC. Effect of dietary copper addition on lipid metabolism in rabbits. Food & Nutrition Research. 2017. 61(1): 1348866. doi: 10.1080/16546628.2017.1348866.

26. Liu L, Fu C, Li FC. Dietary niacin supplementation suppressed hepatic lipid accumulation in rabbits. Asian-Australasian Journal of Animal Sciences. 2016. 29(12):1748-1755.doi: 10.5713/ajas.15.0824

27.Liu L, Xu S, Wang X, Jiao H, Lin H. Peripheral insulin doesn’t alter appetite of broiler chicks. Asian-Australasian Journal of Animal Sciences. 2016. 29(9): 1294-1299. doi: 10.5713/ajas.15.0674.

28.Liu L, Li B, Zhu YL, Li FC. Differential gene expression profiles in fetal skin of rex rabbits with different wool density. World Rabbit Science. 2016. 24(3):223-231. dio: https://doi.org/10.4995/wrs.2016.2335.

29. Liu L, Xu S, Wang X, Jiao H, Zhao J, Lin H. Effect of dexamethasone on hypothalamic expression of appetite-related genes in chickens under different diet and feeding conditions. Journal of Animal Science and Biotechnology. 2016, 7:23. doi: 10.1186/s40104-016-0084-x.

30. Hu X, Liu L*, Song Z, Sheikhahmadi A, Wang Y, Buyse J. Effects of feed deprivation on the AMPK signaling pathway in skeletal muscle of broiler chickens. Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology. 2016. 191:146-154. doi: 10.1016/j.cbpb.2015.10.007. (*co-first author)

31. Liu L, Wang X, Jiao H, Zhao J, Lin H. Glucocorticoids inhibited hypothalamic target of rapamycin in high fat diet-fed chicks. Poultry Science 2015. 94(9): 2221-2227.doi: 10.3382/ps/pev168

32. Yang J, Liu L*, Sheikhahmadi A, Wang Y, Li C, Jiao H, Lin H, Song Z Effects of corticosterone and dietary energy on immune function of broiler chickens. PLoS One. 2015. 10(3): e0119750. doi: 10.1371/journal.pone.0119750.(*co-first author)

33. Liu L, Song Z, Jiao H, Lin H. Glucocorticoids increase NPY gene expression via hypothalamic AMPK signaling in broiler chicks. Endocrinology. 2014. 155(6): 2190-2198. doi: 10.1210/en.2013-1632.34. Liu L, Li HP, Sun XL, Jiao HC, Lin H, Sheikhahmadi A, Wang YF, Song ZG. Effects of acute heat stress on gene expression of brain-gut neuropeptides in broiler chickens (Gallus gallus domesticus). Journal of Animal Science. 2013 91(11): 5194-5201. doi: 10.2527/jas.2013-6538.

35. Liu L, Zhu L. Effect of 24 h fasting on gene expression of AMPK, appetite regulation peptides and lipometabolism related factors in the hypothalamus of broiler chicks. Asian-Australasian Journal of Animal Sciences. 2012. 25(9): 1300-1308. doi: 10.5713/ajas.2012.12153.

36.Song Z, Liu L*, Yue Y, Jiao H, Lin H, Sheikhahmadi A, Everaert N, Decuypere E, Buyse J. Fasting alters protein expression of AMP-activated protein kinase in the hypothalamus of broiler chicks (Gallus gallus domesticus). General and Comparative Endocrinology. 2012. 178(3): 546-555. doi: 10.1016/j.ygcen.2012.06.026. (*Co-first author)

37. Liu L, Song Z, Sheikhahmadi A, Jiao H, Lin H. Effect of corticosterone on gene expression of feed intake regulatory peptides in laying hens. Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology. 2012. 162(4): 81-87. doi: 10.1016/j.cbpb.2012.04.005.

38.Song Z, Liu L*, Sheikhahmadi A, Jiao H, Lin H. Effect of heat exposure on gene expression of feed intake regulatory peptides in laying hens. Journal of Biomedicine and Biotechnology. 2012. 2012:484869. doi: 10.1155/2012/484869. (*Co-first author)

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