魏晴晴

职称：讲师

邮箱：weiqq@sdau.edu.cn

个人主页链接（如果在其他地方有信息较全的个人主页，如ResearchGate，学校的机构知识库等）

个人简介

魏晴晴，女，博士，讲师，2017年毕业于中国农业大学生物学院获理学博士学位，2018年入职山东农业大学威尼斯wns·8885556动物遗传育种与繁殖系。目前主要从事动物体细胞重编程分子机制、胚胎干细胞和诱导多能干细胞多能性维持及定向诱导分化等相关研究。主持山东省自然科学基金1项、省部共建草原家畜生殖调控与繁育国家重点实验室开放课题1项。以第一作者或参与者在Biology of Reproduction、General and Comparative Endocrinology、Nature Communication、Stem Cell Reports、Protein Cell 等SCI期刊发表论文10余篇。

教育经历

2019 - 至今 , 博士后 , 畜牧学, 山东农业大学威尼斯wns·8885556

2013 - 2017 , 理学博士 , 生物化学与分子生物学 , 中国农业大学生物学院

2010 - 2013 , 农学硕士 , 动物遗传育种与繁殖学 , 山东农业大学威尼斯wns·8885556

2006 - 2010 , 农学、文学双学士, 动物科学、英语专业，山东农业大学威尼斯wns·8885556

工作经历

2018 - 至今 , 讲师 , 山东农业大学威尼斯wns·8885556

执教课程

动物分子生物学（本科生）

动物生物技术（本科生）

研究领域

研究方向为动物干细胞与发育生物学，主要包括

1. 利用诱导多能干细胞技术研究体细胞重编程的分子机制；

2. 诱导多能干细胞和胚胎干细胞多能性维持和分化的调控机制研究。

承担的科研项目

主持山东省自然科学基金1项（ZR2019BC065）、省部共建草原家畜生殖调控与繁育国家重点实验室开放课题1项（2021KF0105）。

发表文章、专利

1 Wei, Q., Li, R., Zhong, L., Mu, H., Zhang, S., Yue, L., Xiang, J., Li, En., Zhi, M., and Han, J. (2018). Lineage specification revealed by single-cell gene expression analysis in porcine preimplantation embryos. Biol. Reprod. 99(2), 283-292.

2 Wei, Q., Zhong, L., Zhang, S., Mu, H., Xiang, J., Yue, L., Dai, Y., and Han, J. (2017). Bovine lineage specification revealed by single-cell gene expression analysis from zygote to blastocyst. Biol. Reprod. 97, 5-17.

3 Wei, Q., Zhu, G., Cui, X., Kang, L., Cao, D., and Jiang, Y. (2013). Expression of CCT6A mRNA in chicken granulosa cells is regulated by progesterone. Gen. Comp. Endocrinol. 189, 15-23.

4 Yue L., Pei Y., Zhong L., Henry Yang, Wang Y., Zhang W., Chen N., Zhu Q., Gao Jie., Zhi M., Wen B., Zhang S., Xiang J., Wei Q., Liang H., Cao S., Lou H., Chen Z., Han J. (2020) Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells. Stem Cell Reports. Aug 11;15(2):529-545.

5 Zhang S., Chen T., Chen N., Gao D., Shi B., Kong S., West RC, Yuan Y., Zhi M., Wei Q., Xiang J., Mu H., Yue L., Lei X., Wang X., Zhong L., Liang H., Cao S., Belmonte JCI, Wang H., Han, J. (2019). Self-assembled embryos with three types of blastocyst-derived stem cells. Nature Commu. 10(1):496.

6 Xiang, J., Cao, S., Zhong, L., Wang, H., Pei, Y., Wei, Q., Wen, B., Mu, H., Zhang, S., Yue, L., et al. (2018). Pluripotent stem cells secrete Activin A to improve their epiblast competency after injection into recipient embryos. Protein Cell. 2018 Aug;9(8):717-728.

7 Cao, S., Zhong, L., Mu, H., Wen, B., Zhang, W., Wei, Q., Gao, G., and Han, J. (2017) Long non-coding RNAs involved in the regulatory network during porcine pre-implantation embryonic development and iPSC induction. Sci. Rep. DOI: 10.1038/s41598-018-24863-5.

8 Wang, H., Xiang, J., Zhang, W., Li, J., Wei, Q., Zhong, L., Ouyang, H., and Han, J. (2016). Induction of germ cell-like cells from porcine induced pluripotent stem cells. Sci. Rep. 6, 27256.

9 Pei, Y., Yue, L., Zhang, W., Wang, Y., Wen, B., Zhong, L., Xiang, J., Li, J., Zhang, S., Wang, H., Mu, H., Wei, Q., and Han, J. (2015). Improvement in mouse iPSC induction by Rab32 reveals the importance of lipid metabolism during reprogramming. Sci. Rep. 5, 16539.

10 Zhu, G., Kang, L., Wei, Q., Cui, X., Wang, S., Chen, Y., and Jiang, Y. (2014). Expression and regulation of MMP1, MMP3, and MMP9 in the chicken ovary in response to gonadotropins, sex hormones, and TGFB1. Biol. Reprod. 90, 57.