姓名：杨维仁
职称：教授
邮箱：wryang211@163.com
办公室电话：18605489796
http://202.194.143.43/scholar/scholarDetail/2037.shtml?showHomePage=true
个人简介
杨维仁，男，教授，博士生导师，山东畜牧兽医学会饲料科技专业委员会会长，山东省生猪产业体系岗位专家，泰安市饲料工业协会会长，泰安市政协常委。近年来参加和主持国家“九五”“十五”攻关子题、国家863计划、国家科技支撑计划子课题、山东省自然科学基金等国家及省部级项目10多项。现主持“十四五国家重点研发计划”、“山东省重点研发计划”等科研项目10多项。先后以第一作者或通讯作者在《International Journal of Biological Macromolecules》、《Animal Nutrition》、《Food & Function》、《Ecotoxicology and Environmental Safety》等本领域学术期刊发表SCI论文40余篇。授权“一种甜高粱和田菁混合青贮饲料及其制备方法和应用”等国家发明专利4项；制定山东省地方标准3项；主编、副主编《新编肉鸡饲料配方600例》、《配合饲料工艺学》、《新编仔猪饲料配方600例》等著作10余部。主持完成的“高效安全肉鸡饲料配套技术研究与应用”、“非粮饲料资源发酵关键技术开发及产业化推广”、“饲料原料发酵安全高效创新技术研究与示范应用”等研究成果先后获得山东省科技进步二等奖、青岛市科技进步二等奖、山东省畜牧科学技术奖等奖励10余项，项目成果在新希望六和等多家企业推广。
教育经历
2002- 2004 , 农学博士 , 动物营养与饲料科学 , 中国农业大学
1987 - 1990 , 农学硕士 , 动物营养与饲料科学 , 山东农业大学
1983 - 1987 , 农学学士 , 动物营养学 , 山东农业大学
工作经历
2006 - 至今, 教授 , 山东农业大学
1997 - 2006 , 副教授, 山东农业大学
1993 - 1997 , 讲师, 山东农业大学
1990 - 1993 , 助教, 山东农业大学
荣誉奖励
山东省畜牧科学技术奖一等奖 ,2023
山东省畜牧科学技术奖一等奖 ,2020
山东省科技进步奖二等奖，2015
山东省高校优秀科研成果一等奖，2013
临沂市科技进步奖三等奖，2013
山东省科技进步奖三等奖，2012
临沂市科技进步奖三等奖，2012
临沂市科学技术奖一等奖，2010
临沂市科学技术奖三等奖，2010
山东省农业科学院科学技术进步奖一等奖，2009
山东省农牧渔业丰收奖三等奖，2008
青岛市人民政府青岛市科学三等奖，2007
山东省十大科技成果奖，2000
山东省星火科技一等奖，1998
执教课程
动物营养学（本科生）
动物营养与饲料学，饲料资源开发与利用专题（硕士研究生）
动物营养与饲料科学专题（博士研究生）
研究领域
本实验室主要研究领域：
1. 动物营养与代谢
2. 饲料科学与安全评价
主要围绕饲料资源的价值评定，阐明动物营养与代谢规律，揭示营养素对畜禽（尤其是猪）健康的调控及其作用机制。同时，围绕饲料安全评价，揭示饲料毒素的作用及其机理，开发利用饲料资源。
承担的科研项目：
1.十四五国家重点研发计划“特色非粮饲料资源开发利用关键技术课题（2023YFD1301600）”，60万元，子课题主持
2.山东省重点研发计划（乡村提振计划项目）“生猪绿色智能生产关键技术集成创新与示范（2024TZXD027）”，200万元，主持
3.山东省生猪产业技术体系营养与饲料岗位科学家项目（SDAIT-08-05）,110万元，主持
4.山东省重点研发计划（重大科技创新工程）项目“环境友好型猪禽无抗饲料和替抗养殖关键技术研究与应用（2019JZZY020609）”，40万元，子课题主持
5.山东省重点研发计划（农业良种工程）项目“地方特色优质蛋鸡新品种培育及推广（040311048）”，20万元，子课题主持
6.山东省自然科学基金面上项目“基于转录组学探讨玉米赤霉烯酮诱导仔猪卵巢颗粒细胞线粒体能量代谢的机制（ZR2019MC038）“，20万元，主持
7.山东省农业重大技术协同推广项目”肉牛精准饲喂与产品加工质量控制技术集成与协同推广（040311191）”，8万元，主持
8.产学合作协同育人项目“发酵饲料营养配比优化提升（KGRCYJY2021004）”，5万元，主持
9.横向课题“新型饲料添加剂研究与应用”，106万元，主持
10.横向课题“惠公康（枯草肽）对肉仔鸡生长性能和健康的影响”，10万元，主持
11.横向课题“溢脂宝（溶血磷脂）在肉鸡日粮中应用效果的评价研究”，8万元，主持
发表文章、专利
1. Zihao Liu, Min Liu, Huiru Wang, Pengxiang Qin, Yanjiao Di, Shuzhen Jiang, Yang Li, Libo Huang, Ning Jiao* and Weiren Yang*. Glutamine attenuates bisphenol A-induced intestinal inflammation by regulating gut microbiota and TLR4-p38/MAPK-NF-κB pathway in piglets. Ecotoxicology and Environmental Safety, 2023, 11
2. Liu Heng, Ren Xiaojie, Li Yang, Cao Qingjie, Yang Lijie, Jiang Shuzhen, Fu Jiawei, Gao Jie, Yan Lei, Li Junxun* and Yang Weiren*. Effects of different wheat bran fermentation sources on growth performance, nutrient digestibility, serum antioxidant capacity and fecal microbiota in growing pigs. Frontiers in Veterinary Science, 10:1289010
3. Peng Yuan, Xiaojie Ren, Jiaxing Niu, Yang Liu, Libo Huang, Shuzhen Jiang, Ning Jiao, Xuejun Yuan, Weiren Yang* and Yang Li*. Effects of Dietary Galla Chinensis Tannin Supplementation on Antioxidant Capacity and Intestinal Microbiota Composition in Broilers. Agriculture, 2023, 13(09)
4. Xiaojie Ren, Yan Zhang, Hai Lu, Ning Jiao, Shuzhen Jiang, Yang Li, Junxun Li, Weiren Yang*. Effects of Dietary Bacillus subtilis BC02 Supplementation on Growth Performance, Antioxidant Capacity and Cecal Microbes in Broilers. Agriculture, 2023, 13（08）
5. Yuechang Ren, Yaping Liu, Kexin Jiang, Linkui Li, Ning Jiao, Zhengqi Zhu, Kaiying Zhang, Shuzhen Jiang, Weiren Yang* and Yang Li*.Effects of Low-Phosphorus Diets Supplemented with Phytase on the Production Performance,Phosphorus-Calcium Metabolism, and Bone Metabolism of Aged Hy-Line Brown Laying Hens, Animal, 2023，13 (06)
6. Peng Yuan, Haitao Xu, Yuanfei Ma, Jiaxing Niu, Yang Liu, Libo Huang, Shuzhen Jiang, Ning Jiao, Xuejun Yuan, Weiren Yang* and Yang Li* 1Effects of dietary Galla Chinensis tannin supplementation on immune function and liver health in broiler chickens challenged with lipopolysaccharide，Frontiers in Veterinary Science, 10.
7. Hengchen Liu, Jianli Sun, Shuzhen Jiang, Ning Jiao, Libo Huang, Xuejun Yuan, Qinglin Guan, Yang Li* and Weiren Yang* Effects of Dietary Isoleucine Supplementation on the Production Performance, Health Status and Cecal Microbiota of Arbor Acre Broiler Chickens, Microorganisms, 2023, 11
8. Xing Chen, Xiangming Ma, ChongWu Yang, Shuzhen Jiang, Libo Huang, Yang Li, Fan Zhang, Ning Jiao* and Weiren Yang*. Low level of dietary organic trace elements improve the eggshell strength, trace element utilization, and intestinal function in late-phase laying hens. Frontiers in veterinary science, 2022, 9.
9. Boyang Wan, Libo Huang, Changwei Jing, Yang Li, Ning Jiao, Ming Liang, Shuzhen Jiang* and Weiren Yang*. Zearalenone promotes follicle development through activating the SIRT1/PGC-1α signaling pathway in the ovaries of weaned gilts. Journal of Animal Science, 2022, 100: 1-12.
3. Chang Mengru, Li Mingcong, Li Min, Xie Yuhuai, Li Yan, Yang Weiren*, Gao Zheng*. Changes of gut microbiota in pregnant sows induced by 5-Aminolevulinic acid, Research in Veterinary Science, 2021, 136:57-65
10. Lulu Ma, Yanping Jiang, Fuguang Lu, Shujing Wang, Mei Liu, Faxiao Liu, Libo Huang, Yang Li, Ning Jiao, Shuzhen Jiang, Xuejun Yuan* and Weiren Yang* Quantitative Proteomic Analysis of Zearalenone-Induced Intestinal Damage in Weaned Piglets. Toxins, 2022, 14(10)
11. Junhui Li, Yuhuai Xie, Min Li, Shaotao Zhang, Qun Cheng, Weiren Yang* Effects of Feeding 5-Aminolevulinic Acid on Iron Status in Weaned Rats from the Female Rats during Gestation and Lactation. Animals, 2022, 12(20)
12. Yang Liu, Yang Li*, Jiaxing Niu, Hua Liu, Ning Jiao, Libo Huang, Shuzhen Jiang, Weiren Yang*. Effects of dietary Macleaya Cordata extract containing isoquinoline alkaloids supplementation as an alternative to antibiotics in the diets on growth performance and liver health of broiler chickens. Frontiers in Veterinary Science, 2022, 950174.
13. Yang Liu, Qinjin Wang, Hua Liu, Jiaxing Niu, J Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang*, Yang Li*. Effects of dietary Bopu powder supplementation on intestinal development and microbiota in broiler chickens. Frontiers in Microbiology, 2022, 13: 975056.
14. Junwei Li, Yang Liu, Jiaxing Niu, Changwei Jing, Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang*, Yang Li*. Supplementation with paraformic acid in the diet improved intestinal development through modulating intestinal inflammation and microbiota in broiler chickens. Frontiers in Microbiology, 2022, 13: 3515.
15. Jiaxing Niu, Qinjin Wang, Changwei Jing, Yang Liu, Hua Liu, Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang*, Yang Li*. Dietary Galla Chinensis tannic acid supplementationin the diets improves growth performance, immune function and liver health status of broiler chicken. Frontiers in Veterinary Science, 2022, 9:1024430.
16. Changwei Jing, Jiaxing Niu, Yang Liu, Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang*, Yang Li*. Tannic acid extracted from Galla chinensis supplementation in the diet improves intestinal development through suppressing inflammatory responses via blockage of NF-κB in broiler chickens. Animals, 2022, 12(18):2397.
17. Zhang Quanwei, Huang Libo, Leng Bo, Li Yang, Jiao Ning, Jiang Shuzhen, Yang Weiren*, Yuan Xuejun*. Zearalenone affect the intestinal villi associated with the distribution and the expression of ghrelin and proliferating cell nuclear antigen in weaned gilts. Toxins, 2021, 13:736.
18. Pengfei Zhang, Changwei Jing, Ming Liang, Shuzhen Jiang, Libo Huang, Ning Jiao, Yang Li*and Weiren Yang*. Zearalenone exposure triggered cecal physical barrier injury through the TGF-β1/Smads signaling pathway in weaned piglets. Toxins, 2021, 13:902.
19. Shaotao Zhang, Yuhuai Xie, Min Li, Haitao Yang, Shiyin Li, Junhui Li, Qingqing Xu, Weiren Yang*, Shuzhen Jiang. Effects of different selenium sources on meat quality and shelf life of fattening pigs. Animals, 2020, 10(4): 615.
20. Qun Cheng, Shuzhen Jiang, Libo Huang, Yuxi Wang, Weiren Yang*, Zaibin Yang, Jinshan Ge. Effects of zearalenone-induced oxidative stress and Keap1–Nrf2 signaling pathway-related gene expression in the ileum and mesenteric lymph nodes of post-weaning gilts. Toxicology, 2020, 429: 152337.
21. Qun Cheng, Shuzhen Jiang, Libo Huang, Weiren Yang*, and Zaibin Yang. Zearalenone regulates key factors of the Keap1-Nrf2 signaling pathway in duodenum of post-weaning gilts. Animal Bioscience, 2020, 34(8):1403-1414.
22. Yuhuai Xie, Lixue Wang, Hua Sun, Qinghui Shang, Yuxi Wang, Guiguo Zhang, Weiren Yang* and Shuzhen Jiang*. A polysaccharide extracted from alfalfa activates splenic B cells by TLR4 and acts primarily via the MAPK/p38 pathway. Food &Function, 2020, 11(10): 9035-9047.
23. Yuhuai Xie, Qing Zhang, Lixue Wang, Yuxi Wang, Zhenfeng Cheng, Zaibin Yang, Weiren Yang*. The effects of partially or completely substituted dietary zinc sulfate by lower levels of zinc methionine on growth performance, apparent total tract digestibility, immune function, and visceral indices in weaned piglets. Animals. 2019, 9(5): 236.
24. Yuhuai Xie, Lixue Wang, Hua Sun, Yuxi Wang, Zaibin Yang, Guiguo Zhang, Weiren Yang*. Immunomodulatory, antioxidant and intestinal morphology-regulating activities of alfalfa polysaccharides in mice. International Journal of Biological Macromolecules, 2019, 133: 1107-1114.
25. Qun Cheng, Shuzhen Jiang, Libo Huang, Jinshan Ge, Yuxi Wang, and Weiren Yang*. Zearalenone induced oxidative stress in the jejunum in postweaning gilts through modulation of the Keap1–Nrf2 signaling pathway and relevant genes. Journal of animal science, 2019, 97(4): 1722-1733.
26. Yan Li, Weiren Yang*, Donghua Dong, Shuzhen Jiang, Zaibin Yang, Yuxi Wang. Effect of different sources and levels of iron in the diet of sows on iron status in neonatal pigs. Animal Nutrition, 2018, 4(2): 197-202.
27. Yuhuai Xie, Lixue Wang, Hua Sun, Yuxi Wang, Zaibin Yang, Guiguo Zhang, Shuzhen Jiang, Weiren Yang*. Polysaccharide from alfalfa activates RAW 264.7 macrophages through MAPK and NF-κB signaling pathways. International Journal of Biological Macromolecules 2019, 126: 960-968.
28. Yuhuai Xie, Chongyu Zhang, Lixue Wang, Qinghui Shang, Guiguo Zhang, Weiren Yang*. Effects of dietary supplementation of Enterococcus faecium on growth performance, intestinal morphology, and selected microbial populations of piglets. Livestock Science, 2018, 210: 111-117.
29. Caiyun Yu∗, Jiandong Wei, Chongwu Yang, Zaibin Yang*, Weiren Yang*, and Shuzhen Jiang. Effects of star anise (Illicium verum Hook.f.) essential oil on laying performance and antioxidant status of laying hens. Poultry Science 2018, 97(11): 3957-3966.
30. Cheng, Q., Jiang, S. Z., Li, S. Q., Wang, Y. X., Zhang, C. Y., & Yang, W. R*. Effects of low-dose zearalenone-contaminated diets with or without montmorillonite clay adsorbent on nutrient metabolic rates, serum enzyme activities, and genital organs of growing-laying hens. Journal of Applied Poultry Research, 2017, 26(3): 367-375.
31. Guiguo Zhang, Zaibin Yang, Y. Wang, Weiren Yang*, and H. J. Zhou*. Effects of dietary supplementation of multi-enzyme on growth performance, nutrient digestibility, small intestinal digestive enzyme activities, and large intestinal selected microbiota in weanling pigs. Journal of animal science, 2014, 92(5): 2063-2069.
32. Chengcheng Li, Baohua Xu, Yuxi Wang, Zaibin Yang & Weiren Yang*. Protein content in larval diet affects adult longevity and antioxidant gene expression in honey bee workers. Entomologia experimentalis et applicate 2014, 151(1): 19-26.
33. Guiguo Zhang, Zaibin Yang, Y. Wang, and Weiren Yang*. Effects of Astragalus membranaceus root processed to different particle sizes on growth performance, antioxidant status, and serum metabolites of broiler chickens. Poultry science, 2013, 92(1): 178-183.
34. Zuo, Z. Y., Weiren Yang*, Wang, Y., Zaibin Yang, Shuzhen Jiang, & Guiguo Zhang. Effects of Astragalus membranaceus on laying performance and antioxidant status of laying hens. Poultry Science Association, 2012 2012, 21(2): 243-250.
35. Chengcheng Li, Baohua Xu, Yuxi Wang, Qianqian Feng, Weiren Yang*. Effects of dietary crude protein levels on development, antioxidant status, and total midgut protease activity of honey bee (Apis mellifera ligustica). Apidologie, 2012, 43(5): 576-586.
36. H. F. Wang, W. R. Yang*, H. W. Yang, Y. Wang, Z. B. Yang , S. Z. Jiang & G. G. Zhang. Effects of Astragalus membranaceus on growth performance, carcass characteristics, and antioxidant status of broiler chickens. Acta Agriculturae Scandinavica, Section A — Animal Science, 2010(3).
37. Yang, W. R., Sun, H., Wang, Q. Y., Liu, F. X., & Yang, Z. B*. Effects of rumen-protected methionine on dairy performance and amino acid metabolism in lactating cows. American Journal of Animal and Veterinary Sciences, 2010, 5(1): 1-7.
38. H. Sun, W.R. Yang*, Z.B. Yang, Y. Wang, S.Z. Jiang and G.G. Zhang. Effects of betaine supplementation to methionine deficient diet on growth performance and carcass characteristics of broilers. American Journal of Animal and Veterinary Sciences, 2008(3).
39. 任跃昌,江珂欣,陈正平,马璐璐,李林葵,万波扬,张鹏飞,杨维仁*.发酵饲料对蛋鸡生产性能、蛋品质及血清生化指标的影响，饲料研究，2022，45（06），38-42.
40. 任跃昌,邓夕民,陈正平,单忠芳,刘亚萍,马璐璐,张鹏飞,万波扬,杨维仁*.不同磷源和水平对69～78周龄蛋鸡产蛋性能和骨代谢的影响，动物营养学报，2022，34（06），3604-3614
41. 李军辉,姜淑贞,王长波,杨维仁*.5-氨基乙酰丙酸的生物学功能及其在畜禽生产中的应用，动物营养学报，2022，35（01），120-126
42. 任跃昌,赵恬玉,李林葵,朱政奇,张凯瑛,马璐璐,张鹏飞,孙作为,杨维仁*.枯草芽孢杆菌对87～93 w蛋鸡生产性能、蛋品质、血清生化的影响，中国饲料，2023，05，42-46
43. 陈星,卢文标,梁明,杜文涛,张帆,万波扬,焦宁,杨维仁*.包被微量元素对产蛋后期蛋鸡抗氧化能力和微量元素沉积的影响，中国畜牧杂志，2023，59（05），211-216
44. 李军辉,解玉怀,张少涛,李敏,李世印,徐青青,张小东,张成喜,杨维仁*.饲粮中添加水解单宁酸对肉鸡生长性能及肠道健康的影响[J]. 动物营养学报. 2021, 33(05):2642-2651.
45. 张少涛,李敏,解玉怀,程振峰,杨维仁*. 硒代蛋氨酸的生物学功能及其在猪生产中的应用[J]. 中国畜牧兽医. 2020(09).
46. 徐青青,张少涛,杨海涛,李敏,李军辉,朱成杰,殷若新,杨维仁*.乳酸型复合酸化剂对白羽肉鸡生长性能、养分利用率、肠道指标和鸡舍空气质量的影响[J]. 动物营养学报. 2020(11).
47. 徐明涛,冯蕾,陈鹏,姜淑贞,黄丽波,侯衍猛,成子强,杨在宾,葛利江,杨维仁*.杜仲叶提取物对三元杂交断奶仔猪小肠内ghrelin表达的影响[J]. 中国兽医学报. 2018(10).
48. 程群,姜淑贞,陈宁波,黄丽波,张桂国,杨维仁*.镰刀菌毒素对断奶仔猪脾脏抗氧化能力和白细胞介素-1β、白细胞介素-6分布和表达的影响[J]. 动物营养学报. 2017(09).