刘建柱简历

姓名: 刘建柱

职称：教授

邮箱：liujz@sdau.edu.cn

办公室电话：0538-8249222-8201

个人简介

刘建柱，博士，教授，博士生导师、博士后合作导师，1512二层次专家。中共山东农业大学威尼斯wns·8885556党委委员，教授委员会委员，兽医专业学位点点长、中华人民共和国执业兽医师出题、审题专家，第六、七届中国兽药典委员会委员，全国专业标准化技术委员会委员，全国畜禽质量标准创新中心专家，山东省优秀本科、硕士、博士学位论文指导教师。曾任威尼斯wns·8885556临床兽医学系系主任，山东农业大学动物保健医院院长。主编《动物临床诊断学》等国家级规划教材4部，主编《宠物医师临床急救手册》（执业兽医师培训教材）等科普图书18本，先后主持国家自然基金，山东省自然基金，“十三五”重点研发计划项目、农业部行业专项子课题、归国留学基金项目、博士后特别资助等项目20余项。现已在 Journal of Hazardous Materials，Biosens Bioelectron，Emerging Microbes & Infections，Biomed Pharmacother，Chemosphere， Carbohydr Polym. Human & Experimental Toxicology，Vaccine、Veterinary Parasitol，Research in Veterinary science，等期刊杂志上发表研究性论文130余篇，其中SCI收录论文100余篇，最高影响因子10.538。

教育经历

1995-1999 黑龙江八一农垦大学 威尼斯wns·8885556 本科 农学学士（兽医学）

2000-2003 黑龙江八一农垦大学 威尼斯wns·8885556 硕士 农学硕士（预防兽医学）

2003-2006 韩国 忠南大学 兽医学院  博士 兽医学博士（临床兽医学-小动物内科学）

工作经历

2014-今 山东农业大学 威尼斯wns·8885556 教授 博士生导师

2006-2014 山东农业大学 威尼斯wns·8885556 副教授 硕士生导师

1999-2000 黑龙江省海林市畜牧局   检疫员

荣誉奖励

国家优秀自费留学生奖学金获得者 , 2005

执教课程

动物临床诊断学，特种经济动物疾病学，宠物观赏与管理（本科生）

现代兽医临床诊疗技术，现代动物内科与诊断学（研究生）

研究领域

    本实验室主要研究领域：

　　1. 临床微生物学

　　2. 动物营养代谢病与中毒病

　　3. 小动物疾病学

承担的科研项目

 1、国家自然基金，Parkin在Cr（VI）致鸡肝细胞线粒体自噬中的调控及机制研,31872535。

2、山东省自然基金，基于ATF6介导Cr(VI)致DF1细胞凋亡的调控机制研究，ZR201709250352，

3、“十三五”重点研发计划，犬猫心电图诊断及心电监护技术与规程研究，2016YFD0501007。

4、“十三五”重点研发计划，镉、铬、砷等重金属在畜禽机体上危害与残留特征及其防控技术研究，2016YFD0501208。

5、山东省青年科学家奖励基金，猪附红细胞体MSG1基因人工定点诱变及对其抗原性的影响，BS2009NY007。

发表文章、专利

一．论文

1. Wang X, Liu M, Geng N, Du Y, Li Z, Gao X, Han B, Liu J, Liu         Y.Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome.Vet Res. 2022 Feb 5;53(1):10. doi: 10.1186/s13567-022-01027-y.PMID: 35123552 (IF 3.683) 

 2. Wang C, Qi C, Liu M, Wang L, Cheng G, Li L, Xing Y, Zhao X, Liu J.Protective effects of agrimonolide on hypoxia-induced H9c2 cell injury by maintaining mitochondrial homeostasis.J Cell Biochem. 2021 Nov 1. doi: 10.1002/jcb.30169. Online ahead of print.PMID: 34724244 (IF4.429) 

 3.Wang R, Zhang W, Wang L, Geng N, Wang X, Zhang M, Liu J, Liu Y, Han B. Intracellular Staphylococcus aureus inhibits autophagy of bovine mammary epithelial cells through activating p38α.J Dairy Res. 2021 Aug;88(3):293-301. doi: 10.1017/S0022029921000649.PMID: 34425921 (IF 1.904)

 4. Xing Y, Wang L, Xu G, Guo S, Zhang M, Cheng G, Liu Y, Liu J. Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.Res Vet Sci. 2021 Nov;140:18-25. doi: 10.1016/j.rvsc.2021.08.004. Epub 2021 Aug 8.PMID: 34391058(IF 2.534)

 5.Zou X, Jiang S, Zhang M, Hu H, Wu X, Liu J, Jin M, Cheng H.Effects of Bacillus subtilis on Production Performance, Bone Physiological Property, and Hematology Indexes in Laying Hens.Animals (Basel). 2021 Jul 8;11(7):2041. doi: 10.3390/ani11072041.PMID: 34359169 (IF 2.752) 

 6.Liu K, Cui Y, Li H, Qi C, Cheng G, Gao X, Zhang Z, Liu Y, Liu J. Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.Biol Trace Elem Res. 2021 Jul 30. doi: 10.1007/s12011-021-02850-8. Online ahead of print.PMID: 34327609 (IF 3.738)

 7.Wang Y, Wang L, Wang X, Cheng G, Xing Y, Zhang M, Zhang P, Liu J.Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.Biol Trace Elem Res. 2022 Mar;200(3):1312-1320. doi: 10.1007/s12011-021-02715-0. Epub 2021 Apr 13.PMID: 33851329(IF 3.738)

 8.Guo S, Wang X, Wang L, Cheng G, Zhang M, Xing Y, Zhao X, Liu Y, Liu J.Inflammatory injury and mitophagy of the brain in chicken exposed to Cr(VI).Environ Sci Pollut Res Int. 2021 Aug;28(31):42353-42361. doi: 10.1007/s11356-021-13675-2. Epub 2021 Apr 4.PMID: 33813707(IF 4.223)

 9.Zhu Y, Wang L, Yu X, Jiang S, Wang X, Xing Y, Guo S, Liu Y, Liu J.Cr(VI) promotes tight joint and oxidative damage by activating the Nrf2/ROS/Notch1 axis.Environ Toxicol Pharmacol. 2021 Jul;85:103640. doi: 10.1016/j.etap.2021.103640. Epub 2021 Mar 20.PMID: 33757840(IF 4.860)

 10.Tian B, Cai D, Li W, Bu Q, Wang M, Ye G, Liu J, Wang Y, Gou L, Yi J, Zuo Z. Identification and genotyping of a new subtype of bovine viral diarrhea virus 1 isolated from cattle with diarrhea.Arch Virol. 2021 Apr;166(4):1259-1262. doi: 10.1007/s00705-021-04990-7. Epub 2021 Feb 13.PMID: 33582856 (IF 2.574)

11.Wang X, Su F, Yu X, Geng N, Li L, Wang R, Zhang M, Liu J, Liu Y, Han       B. RNA-Seq Whole Transcriptome Analysis of Bovine Mammary Epithelial Cells in Response to Intracellular Staphylococcus aureus.Front Vet Sci. 2020 Dec 7;7:642. doi: 10.3389/fvets.2020.00642. eCollection 2020.PMID: 33426011(IF 3.412)

 12.Zhang S, Zhao X, Hao J, Zhu Y, Wang Y, Wang L, Guo S, Yi H, Liu Y, Liu J.The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.J Hazard Mater. 2021 May 15;410:124607. doi: 10.1016/j.jhazmat.2020.124607. Epub 2020 Nov 19.PMID: 33243643(IF 10.588)

 13. Hao J, Song Y, Tian B, Qi C, Li L, Wang L, Xing Y, Zhao X, Liu J.Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.Ecotoxicol Environ Saf. 2020 Oct 1;202:110901. doi: 10.1016/j.ecoenv.2020.110901. Epub 2020 Jun 25.PMID: 32593805(IF 6.291)

 14.Zhang P, Wang AP, Yang HP, Ai L, Zhang HJ, Wang YM, Bi YL, Fan HH, Gao J, Zhang HY, Liu JZ.Apelin-13 attenuates high glucose-induced calcification of MOVAS cells by regulating MAPKs and PI3K/AKT pathways and ROS-mediated signals.Biomed Pharmacother. 2020 Aug;128:110271. doi: 10.1016/j.biopha.2020.110271. Epub 2020 May 22.PMID: 32450527(IF 6.529)

 15.Wang Y, Wang X, Wang L, Cheng G, Zhang M, Xing Y, Zhao X, Liu Y, Liu J. Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).Biol Trace Elem Res. 2021 Feb;199(2):703-711. doi: 10.1007/s12011-020-02176-x. Epub 2020 May 21.PMID: 32440992(IF 3.738)

 16.Geng N, Wang X, Yu X, Wang R, Zhu Y, Zhang M, Liu J, Liu Y.Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.Front Immunol. 2020 May 5;11:746. doi: 10.3389/fimmu.2020.00746. eCollection 2020.PMID: 32431700(IF 7.561)

 17. Wang Y, Hao J, Zhang S, Li L, Wang R, Zhu Y, Liu Y, Liu J.Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.Environ Sci Pollut Res Int. 2020 Jun;27(18):22980-22988. doi: 10.1007/s11356-020-08544-3. Epub 2020 Apr 23.PMID: 32329004(IF 4.223)

 18. Xu Y, Wang X, Geng N, Zhu Y, Zhang S, Liu Y, Liu J.Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.Ecotoxicol Environ Saf. 2020 May;194:110414. doi: 10.1016/j.ecoenv.2020.110414. Epub 2020 Mar 6.PMID: 32151870(IF  6.291)

 19.Geng N, Liu K, Lu J, Xu Y, Wang X, Wang R, Liu J, Liu Y, Han B.Autophagy of bovine mammary epithelial cell induced by intracellular Staphylococcus aureus.J Microbiol. 2020 Apr;58(4):320-329. doi: 10.1007/s12275-020-9182-8. Epub 2020 Feb 26.PMID: 32103442(IF 3.422)

 20.Wang S, Geng N, Zhou D, Qu Y, Shi M, Xu Y, Liu K, Liu Y, Liu J.Oral Immunization of Chickens With Recombinant Lactobacillus plantarum Vaccine Against Early ALV-J Infection.Front Immunol. 2019 Oct 2;10:2299. doi: 10.3389/fimmu.2019.02299. eCollection 2019.PMID: 31632395(IF 7.561) 

 21.Wang C, Cheng G, Yang S, Li L, Zhang Y, Zhao X, Liu J.Protective effects of Platycodon grandiflorus polysaccharides against apoptosis induced by carbonyl cyanide 3-chlorophenylhydrazone in 3D4/21 cells.Int J Biol Macromol. 2019 Dec 1;141:1220-1227. doi: 10.1016/j.ijbiomac.2019.09.086. Epub 2019 Sep 12.PMID: 31521659 (IF 6.953)

 22.Lu J, Liu K, Qi M, Geng H, Hao J, Wang R, Zhao X, Liu Y, Liu J. Effects of Cr(VI) exposure on electrocardiogram, myocardial enzyme parameters, inflammatory factors, oxidative kinase, and ATPase of the heart in Chinese rural dogs.Environ Sci Pollut Res Int. 2019 Oct;26(29):30444-30451. doi: 10.1007/s11356-019-06253-0. Epub 2019 Aug 22.PMID: 31440970(IF 4.223)

 23.Liu K, Chen P, Lu J, Zhu Y, Xu Y, Liu Y, Liu J.Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.Biol Trace Elem Res. 2020 Apr;194(2):570-580. doi: 10.1007/s12011-019-01795-3. Epub 2019 Jul 1.PMID: 31264128(IF3.738)

 24.Cheng J, Xu Y, Zhou D, Liu K, Geng N, Lu J, Liu Y, Liu J.Novel carbon quantum dots can serve as an excellent adjuvant for the gp85 protein vaccine against avian leukosis virus subgroup J in chickens.Poult Sci. 2019 Nov 1;98(11):5315-5320. doi: 10.3382/ps/pez313.PMID: 31198967(IF 2.425)

 25.Zhu Y, Xu G, Chen P, Liu K, Xu Y, Liu Y, Liu J. Effects of Cr(VI)-induced calcium-sensing receptor activation on DF-1 cell pyroptosis.Ecotoxicol Environ Saf. 2019 Sep 15;179:257-264. doi: 10.1016/j.ecoenv.2019.04.084. Epub 2019 May 1.PMID: 31054379(IF  6.291)

 26.Chen P, Geng N, Zhou D, Zhu Y, Xu Y, Liu K, Liu Y, Liu J.The regulatory role of COX-2 in the interaction between Cr(VI)-induced endoplasmic reticulum stress and autophagy in DF-1 cells.Ecotoxicol Environ Saf. 2019 Apr 15;170:112-119. doi: 10.1016/j.ecoenv.2018.11.120. Epub 2018 Dec 4.PMID: 30529609 (IF 6.291)

 27.Xie N, Geng N, Zhou D, Xu Y, Liu K, Liu Y, Liu J.Protective effects of anthocyanin against apoptosis and oxidative stress induced by arsanilic acid in DF-1 cells.Mol Biol Rep. 2019 Feb;46(1):301-308. doi: 10.1007/s11033-018-4472-5. Epub 2018 Nov 28.PMID: 30488373 (IF 1.595)

 28.Li G, Niu X, Yuan S, Liang L, Liu Y, Hu L, Liu J, Cheng Z. Emergence of Morganella morganii subsp. morganii in dairy calves, China.Emerg Microbes Infect. 2018 Oct 24;7(1):172. doi: 10.1038/s41426-018-0173-3.PMID: 30353002 (IF 6.291)

 29. Fan W, Xu Y, Zhang P, Chen P, Zhu Y, Cheng Z, Zhao X, Liu Y, Liu J.Analysis of molecular evolution of nucleocapsid protein in Newcastle disease virus.Oncotarget. 2017 Sep 28;8(57):97127-97136. doi: 10.18632/oncotarget.21373. eCollection 2017 Nov 14.PMID: 29228598 (IF 5.123)

 30.Zhao X, Wang Y, Yan P, Cheng G, Wang C, Geng N, Wang X, Liu J.Effects of Polysaccharides from Platycodon grandiflorum on Immunity-Enhancing Activity In Vitro. Molecules. 2017 Nov 7;22(11):1918. doi: 10.3390/molecules22111918.PMID: 29112148(IF 4.411)

 31.Fan W, Zheng P, Wang Y, Hao P, Liu J, Zhao X.Analysis of immunostimulatory activity of polysaccharide extracted from Yu-Ping-Feng in vitro and in vivo.Biomed Pharmacother. 2017 Sep;93:146-155. doi: 10.1016/j.biopha.2017.05.138. Epub 2017 Jun 17.PMID: 28628831(IF6.529)

 32.Zhu Y, Chen P, Wan H, Wang Y, Hao P, Liu Y, Liu J.Selenium-Chromium(VI) Interaction Regulates the Contents and Correlations of Trace Elements in Chicken Brain and Serum.Biol Trace Elem Res. 2018 Jan;181(1):154-163. doi: 10.1007/s12011-017-1038-7. Epub 2017 May 10.PMID: 28493199(IF3.738)

 33.Chen P, Zhu Y, Wan H, Wang Y, Hao P, Cheng Z, Liu Y, Liu J.Effects of the Oral Administration of K2Cr2O7 and Na2SeO3 on Ca, Mg, Mn, Fe, Cu, and Zn Contents in the Heart, Liver, Spleen, and Kidney of Chickens.Biol Trace Elem Res. 2017 Dec;180(2):285-296. doi: 10.1007/s12011-017-0999-x. Epub 2017 Mar 28.PMID: 28353138(IF3.738)

 34.Wang Y, Liu Y, Wan H, Zhu Y, Chen P, Hao P, Cheng Z, Liu J.Moderate selenium dosing inhibited chromium (VI) toxicity in chicken liver.J Biochem Mol Toxicol. 2017 Aug;31(8). doi: 10.1002/jbt.21916. Epub 2017 Mar 21.PMID: 28321998(IF 2.683)

 35.Wan H, Zhu Y, Chen P, Wang Y, Hao P, Cheng Z, Liu Y, Liu J.Effect of various selenium doses on chromium(IV)-induced nephrotoxicity in a male chicken model.Chemosphere. 2017 May;174:306-314. doi: 10.1016/j.chemosphere.2017.01.143. Epub 2017 Jan 31.PMID: 28183056(IF 7.086)

 36.Zheng P, Fan W, Wang S, Hao P, Wang Y, Wan H, Hao Z, Liu J, Zhao X. Characterization of polysaccharides extracted from Platycodon grandiflorus (Jacq.) A.DC. affecting activation of chicken peritoneal macrophages.Int J Biol Macromol. 2017 Mar;96:775-785. doi: 10.1016/j.ijbiomac.2016.12.077. Epub 2017 Jan 2.PMID: 28057573(IF 6.953)

 37.Hao P, Zhu Y, Wang S, Wan H, Chen P, Wang Y, Cheng Z, Liu Y, Liu J.Selenium Administration Alleviates Toxicity of Chromium(VI) in the Chicken Brain.Biol Trace Elem Res. 2017 Jul;178(1):127-135. doi: 10.1007/s12011-016-0915-9. Epub 2016 Dec 24.PMID: 28013456(IF 3.738)

 38.Fan W, Wang Y, Wang S, Cheng Z, Guo H, Zhao X, Liu J. Virulence in Newcastle disease virus: A genotyping and molecular evolution spectrum perspective.Res Vet Sci. 2017 Apr;111:49-54. doi: 10.1016/j.rvsc.2016.12.001. Epub 2016 Dec 7.PMID: 27951521(IF2.534)

 39.Cheng J, Wen S, Wang S, Hao P, Cheng Z, Liu Y, Zhao P, Liu J.gp85 protein vaccine adjuvanted with silica nanoparticles against ALV-J in chickens.Vaccine. 2017 Jan 5;35(2):293-298. doi: 10.1016/j.vaccine.2016.11.077. Epub 2016 Nov 29.PMID: 27912987(IF 3.641)

 40. Liu Y, Hao P, Zhang X, Zhao X, Liu Y, Liu J.Effects of Excess Cr3+ on Trace Element Contents in the Brain and Serum in Chicken.Biol Trace Elem Res. 2017 May;177(1):180-186. doi: 10.1007/s12011-016-0875-0. Epub 2016 Oct 19.PMID: 27761845(IF 3.683)

41.Fan W, Zhang S, Hao P, Zheng P, Liu J, Zhao X.Structure     characterization of three polysaccharides and a comparative study of their immunomodulatory activities on chicken macrophage.Carbohydr Polym. 2016 Nov 20;153:631-640. doi: 10.1016/j.carbpol.2016.07.116. Epub 2016 Jul 28.PMID: 27561535(IF 9.381)

 42.Ma T, Liu Y, Cheng J, Liu Y, Fan W, Cheng Z, Niu X, Liu J.Liposomes containing recombinant E protein vaccine against duck Tembusu virus in ducks.Vaccine. 2016 Apr 27;34(19):2157-63. doi: 10.1016/j.vaccine.2016.03.030. Epub 2016 Mar 23.PMID: 27016654

 43.The immune adjuvant response of polysaccharides from Atractylodis macrocephalae Koidz in chickens vaccinated against Newcastle disease (ND).Zhao X, Sun W, Zhang S, Meng G, Qi C, Fan W, Wang Y, Liu J.Carbohydr Polym. 2016 May 5;141:190-6. doi: 10.1016/j.carbpol.2016.01.013. Epub 2016 Jan 12.PMID: 26877012

 44.Cheng J, Fan W, Zhao X, Liu Y, Cheng Z, Liu Y, Liu J.Oxidative Stress and Histological Alterations of Chicken Brain Induced by Oral Administration of Chromium(III).Biol Trace Elem Res. 2016 Sep;173(1):185-93. doi: 10.1007/s12011-016-0640-4. Epub 2016 Feb 12.PMID: 26873037

 45.Hou M, Zhou D, Li G, Guo H, Liu J, Wang G, Zheng Q, Cheng Z.Identification of a variant antigenic neutralizing epitope in hypervariable region 1 of avian leukosis virus subgroup J.Vaccine. 2016 Mar 8;34(11):1399-404. doi: 10.1016/j.vaccine.2016.01.039. Epub 2016 Feb 2.PMID: 26850757

 46.Liu Y, Zhao X, Zhang X, Zhao X, Liu Y, Liu J.Effects of Oral Administration of CrCl3 on the Contents of Ca, Mg, Mn, Fe, Cu, and Zn in the Liver, Kidney, and Heart of Chicken.Biol Trace Elem Res. 2016 Jun;171(2):459-467. doi: 10.1007/s12011-015-0559-1. Epub 2015 Nov 5.PMID: 26537118 Clinical Trial.

 47.Meng K, Sun W, Cheng Z, Guo H, Liu J, Chai T.First detection of severe fever with thrombocytopenia syndrome virus in the tick species Haemaphysalis concinna in Shandong Province, China.Parasitol Res. 2015 Dec;114(12):4703-7. doi: 10.1007/s00436-015-4718-2. Epub 2015 Sep 8.PMID: 26350381

 48.Wang Y, He J, Yang W, Muhantay G, Chen Y, Xing J, Liu J.Correlation between Heart-type Fatty Acid-binding Protein Gene Polymorphism and mRNA Expression with Intramuscular Fat in Baicheng-oil Chicken.Asian-Australas J Anim Sci. 2015 Oct;28(10):1380-7. doi: 10.5713/ajas.14.0886.PMID: 26323394 Free PMC article.

 49.Liu Y, Liu C, Cheng J, Fan W, Zhang X, Liu J.Growth performance and oxidative damage in kidney induced by oral administration of Cr(III) in chicken.Chemosphere. 2015 Nov;139:365-71. doi: 10.1016/j.chemosphere.2015.07.032. Epub 2015 Jul 24.PMID: 26207879

 50.Yan Z, Fan R, Yin S, Zhao X, Liu J, Li L, Zhang W, Ge L.Protective effects of Ginkgo biloba leaf polysaccharide on nonalcoholic fatty liver disease and its mechanisms.Int J Biol Macromol. 2015 Sep;80:573-80. doi: 10.1016/j.ijbiomac.2015.05.054. Epub 2015 Jun 3.PMID: 26047899

 51.Sun W, Meng K, Qi C, Yang X, Wang Y, Fan W, Yan Z, Zhao X, Liu J.Immune-enhancing activity of polysaccharides isolated from Atractylodis macrocephalae Koidz.Carbohydr Polym. 2015 Aug 1;126:91-6. doi: 10.1016/j.carbpol.2015.03.034. Epub 2015 Mar 26.PMID: 25933527

 52.Wei R, Ma X, Wang G, Guo H, Liu J, Fan L, Cheng Z.Synergistic inhibition of avian leukosis virus subgroup J replication by miRNA-embedded siRNA interference of double-target.Virol J. 2015 Mar 21;12:45. doi: 10.1186/s12985-015-0277-5.PMID: 25889403

 53.Fan WT, Zhao XN, Cheng J, Liu YH, Liu JZ.Oxidative stress and hepatocellular injury induced by oral administration of Cr(3+) in chicken.J Biochem Mol Toxicol. 2015 Jun;29(6):280-7. doi: 10.1002/jbt.21697. Epub 2015 Mar 20.PMID: 25800437

 54.Liu M, Liu Y, Cheng Z, Liu J, Chai T.Effects of chromic chloride on chick embryo fibroblast viability.Toxicol Rep. 2015 Mar 23;2:555-562. doi: 10.1016/j.toxrep.2015.03.007. eCollection 2015.PMID: 28962390

 55.Zhang D, Li H, Zhang Z, Sun S, Cheng Z, Liu J, Zhao P, Ren Q, Guo H.Antibody responses induced by recombinant ALV-A gp85 protein vaccine combining with CpG-ODN adjuvant in breeder hens and the protection for their offspring against early infection.Antiviral Res. 2015 Apr;116:20-6. doi: 10.1016/j.antiviral.2015.01.007. Epub 2015 Jan 28.PMID: 25637708

 56.Liu Y, Ma T, Liu J, Zhao X, Cheng Z, Guo H, Xu R, Wang S.Circulating type 1 vaccine-derived poliovirus may evolve under the pressure of adenosine deaminases acting on RNA.J Matern Fetal Neonatal Med. 2015;28(17):2096-9. doi: 10.3109/14767058.2014.979147. Epub 2014 Nov 14.PMID: 25330844

 57.Liu Y, Ma T, Liu J, Zhao X, Cheng Z, Guo H, Wang S, Xu R.Bioinformatics analysis and genetic diversity of the poliovirus.J Med Microbiol. 2014 Dec;63(Pt 12):1724-1731. doi: 10.1099/jmm.0.081992-0. Epub 2014 Sep 26.PMID: 25261065

 58.Yang D, Zhang Q, Zhang L, Dong H, Jing Z, Li Z, Liu J.Prevalence and risk factors of Giardia doudenalis in dogs from China.Int J Environ Health Res. 2015;25(2):207-13. doi: 10.1080/09603123.2014.915021. Epub 2014 May 12.PMID: 24814763

 59.Zhang L, Cai D, Zhao X, Cheng Z, Guo H, Qi C, Liu J, Xu R, Zhao P, Cui Z.Liposomes containing recombinant gp85 protein vaccine against ALV-J in chickens.Vaccine. 2014 May 1;32(21):2452-6. doi: 10.1016/j.vaccine.2014.02.091. Epub 2014 Mar 10.PMID: 24625339

 60.Meng K, Sun W, Zhao P, Zhang L, Cai D, Cheng Z, Guo H, Liu J, Yang D, Wang S, Chai T.Development of colloidal gold-based immunochromatographic assay for rapid detection of Mycoplasma suis in porcine plasma.Biosens Bioelectron. 2014 May 15;55:396-9. doi: 10.1016/j.bios.2013.12.048. Epub 2013 Dec 31.PMID: 24434494

 61.Wang J, Yang X, Wang Y, Jing Z, Meng K, Liu J, Guo H, Xu R, Cheng Z.Genetic diversity and phylogenetic analysis of Tams1 of Theileria annulata isolates from three continents between 2000 and 2012.Cent Eur J Immunol. 2014;39(4):476-84. doi: 10.5114/ceji.2014.47732. Epub 2014 Dec 15.PMID: 26155166 

 62.Cai L, Shen Y, Wang G, Guo H, Liu J, Cheng Z.Identification of two novel multiple recombinant avian leukosis viruses in two different lines of layer chicken.J Gen Virol. 2013 Oct;94(Pt 10):2278-2286. doi: 10.1099/vir.0.054239-0. Epub 2013 Jul 24.PMID: 23884361

 63.Dou W, Li H, Cheng Z, Zhao P, Liu J, Cui Z, Liu H, Jing W, Guo H.Maternal antibody induced by recombinant gp85 protein vaccine adjuvanted with CpG-ODN protects against ALV-J early infection in chickens.Vaccine. 2013 Dec 9;31(51):6144-9. doi: 10.1016/j.vaccine.2013.06.058. Epub 2013 Jul 2.PMID: 23831319

 64.Zhou C, Shi Y, Li J, Zhang W, Wang Y, Liu Y, Liu J.The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice.Pak J Pharm Sci. 2013 Jul;26(4):761-5.PMID: 23811455

 65.Zhang L, Wang Y, Cai D, He G, Cheng Z, Liu J, Meng K, Yang D, Wang S.Detection of Anaplasma marginale in Hyalomma asiaticum ticks by PCR assay.Parasitol Res. 2013 Jul;112(7):2697-702. doi: 10.1007/s00436-013-3437-9. Epub 2013 May 2.PMID: 23636309

 66.Wang G, Wang Y, Yu L, Jiang Y, Liu J, Cheng Z. New pathogenetic characters of reticuloendotheliosis virus isolated from Chinese partridge in specific-pathogen-free chickens.Microb Pathog. 2012 Aug;53(2):57-63. doi: 10.1016/j.micpath.2012.04.001. Epub 2012 May 3.PMID: 22579709

 67.Development and evaluation of enzyme-linked immunosorbent assay based on recombinant inorganic pyrophosphatase gene antigen for the detection of Mycoplasma suis antibodies.Liu J, Zhou D, Cheng Z, Wang Z, Wang L, Wang S, Yang D, Chai T.Res Vet Sci. 2012 Aug;93(1):48-50. doi: 10.1016/j.rvsc.2011.08.016. Epub 2011 Sep 22.PMID: 21940024

 68.Wang F, Wang X, Chen H, Liu J, Cheng Z.The critical time of avian leukosis virus subgroup J-mediated immunosuppression during early stage infection in specific pathogen-free chickens.J Vet Sci. 2011 Sep;12(3):235-41. doi: 10.4142/jvs.2011.12.3.235.PMID: 21897096 

 69.Liu Y, He G, Cheng Z, Qi Y, Liu J, Zhang H, Liu G, Shi D, Yang D, Wang S, Wang Z.Seroprevalence of Toxoplasma gondii in dogs in Shandong, Henan, and Heilongjiang Provinces, and in the Xinjiang Uygur Autonomous Region, People's Republic of China.J Parasitol. 2012 Feb;98(1):211-2. doi: 10.1645/GE-2892.1. Epub 2011 Aug 22.PMID: 21859330

 70.Qi C, Zhou D, Liu J, Cheng Z, Zhang L, Wang L, Wang Z, Yang D, Wang S, Chai T. Detection of Babesia divergens using molecular methods in anemic patients in Shandong Province, China.Parasitol Res. 2011 Jul;109(1):241-5. doi: 10.1007/s00436-011-2382-8. Epub 2011 Apr 19.PMID: 21503639

 71. Liu J, Cheng Z, Zhou D, Zhang L, Yan Z, Wang Z, Yang D, Liu Y, Chai T.Synthesis, cloning, and expression of Mycoplasma suis inorganic pyrophosphatase gene using PCR-based accurate synthesis and overlap-extension PCR, and its immunogenicity analysis.Res Vet Sci. 2011 Dec;91(3):e100-2. doi: 10.1016/j.rvsc.2011.02.009. Epub 2011 Mar 22.PMID: 21429540

 72.Cheng Z, Liu J, Cui Z, Zhang L.Tumors associated with avian leukosis virus subgroup J in layer hens during 2007 to 2009 in China.J Vet Med Sci. 2010 Aug;72(8):1027-33. doi: 10.1292/jvms.09-0564. Epub 2010 May 12.PMID: 20467208

 73. Wang L, Wang Z, Liu J.Protective effect of N-acetylcysteine on experimental chronic lead nephrotoxicity in immature female rats.Hum Exp Toxicol. 2010 Jul;29(7):581-91. doi: 10.1177/0960327109357270. Epub 2010 Jan 22.PMID: 20097726

 74.Duan H, Chai T, Liu J, Zhang X, Qi C, Gao J, Wang Y, Cai Y, Miao Z, Yao M, Schlenker G.Source identification of airborne Escherichia coli of swine house surroundings using ERIC-PCR and REP-PCR.Environ Res. 2009 Jul;109(5):511-7. doi: 10.1016/j.envres.2009.02.014. Epub 2009 Apr 5.PMID: 19349045

 75.Chen TT, Qi C, Guo H, Cheng Z, Zhou D, Liu H, Liu J.The effects of Fu Zi on changes in the body heat of dogs.J Acupunct Meridian Stud. 2009 Mar;2(1):71-4. doi: 10.1016/S2005-2901(09)60018-2. Epub 2009 Apr 7.PMID: 20633477

 76.Yan Z, Liu J, Chen T, Cheng Z, Guo H, Wang Z, Wang Y.Treatment of Mycoplasma wenyonii infection in cows with imidocarb dipropionate injection-acupuncture.J Acupunct Meridian Stud. 2008 Dec;1(2):143-8. doi: 10.1016/S2005-2901(09)60035-2.PMID: 20633467

  77.Wang Y, Wang ZY, Liu JZ.[Study on the spread approach in eperythrozoonosis of dairy cow].Zhonghua Liu Xing Bing Xue Za Zhi. 2007 Mar;28(3):311-2.PMID: 17649674 Chinese. No abstract available.

 78.Liu J, Lee YT, Lee SE, Lee JY, Kim DH. Anti-emetic effect of oculo-acupuncture on dogs with xylazine induced vomiting.Am J Chin Med. 2007;35(3):447-53. doi: 10.1142/S0192415X07004965.PMID: 17597503

 79. Liu J, Song KH, You MJ, Son DS, Cho SW, Kim DHThe effect of oculo-acupuncture on recovery from ethylene glycol-induced acute renal injury in dogs..Am J Chin Med. 2007;35(2):241-50. doi: 10.1142/S0192415X07004783.PMID: 17436365

 80.Liu J, Cho SN, Song KH, Kim DH, Kim MC, Cho SW.The effect of oculo-acupuncture on acute hepatic injury induced by carbon tetrachloride in dogs.Am J Chin Med. 2007;35(1):53-61. doi: 10.1142/S0192415X07004618.PMID: 17265550

81.Dayou Shi, Mingchao Liu, Shining Guo, Shenquan Liao, Mingfei Sun, Jianzhu Liu*, Lin Wang, Zhenyong Wang, Shujing Wang, Dubao Yang and Tongjie Chai. Serological survey of canine leptospirosis in Southern China. Pak. Vet. J. 2012, 32(2): 280-282.(IF 1.217)

二．图书出版情况

主编 国家林业和草原局普通高等教育“十三五”规划教材《动物临床诊断学》（第二版），中国林业出版社，2021年1月出版。

主编 科学出版社普通高等教育“十三五”规划教材《特种动物疾病学》，科学出版社，科学出版社，2020年12月出版。

主编 普通高等教育“十二五”规划教材《动物临床诊断学》（第一版），中国林业出版社，2013年7月。

主编 普通高等教育“十二五”规划教材，高等农林院校“十二五”规划教材《特种经济动物疾病防治学》，中国农业大学出版社，2014年6月。

主译：“十二五”国家重点图书出版计划，世界兽医经典著作译丛《动物血液学彩色图谱》，中国农业出版社，2012年9月出版

主编《宠物医师临床急救手册》，（执业兽医师培训教材）中国农业出版社，2014年4月出版。

主编《猪场兽药规范使用手册》，中国农业出版社，2018年12月出版

主编《中兽医良方治鸡病》，机械工业出版社，2019年7月出版

主编《猪病鉴别诊断图谱与安全用药》，机械工业出版社，2017年5月出版

主编《鸭病鉴别诊断图谱与安全用药》，机械工业出版社，2020年6月出版

主编《宠物医师临床影像手册》，（执业兽医师培训教材）中国农业出版社，2017年11月出版。

主编《养殖场处方药速查》，中国农业出版社，2014年3月出版

主编《宠物处方药速查》，中国农业出版社，2014年3月出版

主编《常见猪病诊治图谱及安全用药》，中国农业出版社，2011年4月出版

主编《常见鸡病诊治图谱及安全用药》，中国农业出版社，2011年4月出版

主编《奶牛场技术管理要点和常见疾病防治》，中国农业出版社，2013年1月出版

主编 高等农林院校合编教材《特种经济动物疾病学》，中国农业出版社，2009年出版

副主编《宠物医师临床药物手册》，金盾出版社，2009年出版

副主编《宠物医师临床检验手册》，金盾出版社，2008年出版

参编普通高等教育“十一五”规划教材《动物疾病诊断学》，中国农业出版社，2009年出版

参编普通高等教育“十一五”规划教材《兽医临床诊断学》，中国农业大学出版社，2011年出版

参编普通高等教育“十一五”规划教材《犬猫疾病学》，中国农业大学出版社，2011年出版

参编《小动物内科学》（王九峰教授主编），中国农业出版社，2013年12月出版

参编《家畜内科学》（庞全海教授主编），中国林业出版社（国家“十二五”规划教材），2015年出版

参编《家畜内科学》（黄克和教授主编），中国农业大学出版社（国家“十三五”规划教材），2020年出版